Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.53 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.53 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.53 |
| ▸ | MAOA | P21397 | 5/20 | 0.49 |
| ▸ | ATP1A1 | P05023 | 1/20 | 0.47 |
| ▸ | ATP1B1 | P05026 | 1/20 | 0.47 |
| ▸ | ATP1A3 | P13637 | 1/20 | 0.47 |
| ▸ | ATP1B2 | P14415 | 1/20 | 0.47 |
| ▸ | ATP1A2 | P50993 | 1/20 | 0.47 |
| ▸ | ATP1B3 | P54709 | 1/20 | 0.47 |
| ▸ | FXYD2 | P54710 | 1/20 | 0.47 |
| ▸ | ATP1A4 | Q13733 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | MAOB | P27338 | 2/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11478429 | 0.86 | ADORA3 (0.48) | ADORA3ADORA2AADORA1KMT2AMEN1 | |
| SCHEMBL11483271 | 0.84 | MAOB (0.45) | ADORA3ADORA2AADORA1KMT2AMEN1 | |
| SCHEMBL11491095 | 0.84 | ERAP1 (0.49) | ADORA3ADORA2AADORA1KMT2AMEN1 | |
| SCHEMBL11480829 | 0.81 | ABCG2 (0.61) | ADORA3ADORA2AADORA1MAOBKDM4E | |
| SCHEMBL11477991 | 0.81 | MAOB (0.54) | MAOAKMT2AMEN1MAOBKDM4E | |
| SCHEMBL8492619 | 0.79 | ATP1A1 (0.56) | ADORA3ADORA2AADORA1MAOAATP1A1 | |
| SCHEMBL669375 | 0.78 | MAOB (0.70) | KMT2AMEN1MAOBKDM4EPKM | |
| SCHEMBL29466790 | 0.78 | MAOB (0.70) | KMT2AMEN1MAOBKDM4EPKM | |
| SCHEMBL26779869 | 0.75 | ESR2 (0.64) | ADORA3ADORA2AADORA1MAOAATP1A1 | |
| SCHEMBL11479865 | 0.75 | CYP3A4 (0.58) | ADORA3ADORA2AADORA1MAOAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4230850-A | HYPOTENSIVE AGENTS, VASODILATION | LIPHA, LYONNAISE INDUSTRIELLE PHARMACEUTIQUE (FR) | 1980-10-28 | — | — | US | disclosed |