Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | DOT1L | Q8TEK3 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | FEN1 | P39748 | 1/20 | 0.33 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | RORC | P51449 | 3/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1127740 | 0.76 | ALDH1A1 (0.46) | ALDH1A1MEN1TSHRKMT2ANPC1 | |
| SCHEMBL4719409 | 0.74 | CDC25B (0.51) | MEN1KMT2AMAPTGAAL3MBTL1 | |
| SCHEMBL2575884 | 0.74 | DOT1L (0.40) | ALDH1A1DOT1LCYP1A2PBRM1CES2 | |
| SCHEMBL49732 | 0.73 | MGAM (0.42) | ALDH1A1KDM4EMEN1TSHRKMT2A | |
| SCHEMBL1181527 | 0.72 | PARP1 (0.41) | ALDH1A1KDM4ETSHRHSD17B10HPGD | |
| SCHEMBL758982 | 0.72 | ALDH1A1 (0.38) | ALDH1A1KDM4EMEN1KMT2ACYP1A2 | |
| SCHEMBL4719862 | 0.71 | KDM4E (0.51) | ALDH1A1KDM4EMEN1KMT2AHSD17B10 | |
| SCHEMBL9726458 | 0.70 | ALDH1A1 (0.67) | ALDH1A1DOT1LTSHRCYP1A2FEN1 | |
| SCHEMBL2167038 | 0.68 | TSHR (0.42) | ALDH1A1KDM4EMEN1TSHRKMT2A | |
| SCHEMBL12984354 | 0.68 | SMN1; SMN2 (0.38) | ALDH1A1KDM4EMEN1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0007508-A2 | Acylphosphinoxide compounds, their preparation and their use | BASF Aktiengesellschaft (DE) | 1980-02-06 | — | — | EP | disclosed |