Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.59 |
| ▸ | LTA4H | P09960 | 1/20 | 0.58 |
| ▸ | HTR1D | P28221 | 1/20 | 0.50 |
| ▸ | HTR1B | P28222 | 1/20 | 0.50 |
| ▸ | HTR7 | P34969 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 8/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | DRD1 | P21728 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL111078 | 0.86 | LTA4H (0.72) | PRMT6LTA4HHTR1DHTR1BKCNH2 | |
| SCHEMBL15244867 | 0.80 | HTR7 (0.53) | HTR7TAAR1DRD2DRD1HTR2C | |
| SCHEMBL477487 | 0.79 | PRMT6 (0.63) | PRMT6LTA4HKCNH2FFAR1HDAC1 | |
| SCHEMBL7499623 | 0.79 | PRMT6 (0.63) | PRMT6LTA4HKCNH2FFAR1DRD2 | |
| SCHEMBL158066 | 0.79 | PRMT6 (0.68) | PRMT6LTA4HKCNH2FFAR1HDAC1 | |
| SCHEMBL4171352 | 0.79 | PRMT6 (0.63) | PRMT6LTA4HKCNH2FFAR1DRD2 | |
| SCHEMBL7076547 | 0.78 | PRMT6 (0.57) | PRMT6LTA4HFFAR1 | |
| SCHEMBL1334921 | 0.77 | KCNH2 (0.59) | PRMT6LTA4HKCNH2CYP17A1CYP11B1 | |
| SCHEMBL21408614 | 0.76 | PRMT6 (0.64) | PRMT6LTA4HHTR1DHTR1BHTR7 | |
| SCHEMBL6601600 | 0.76 | PRMT6 (0.64) | PRMT6LTA4HKCNH2FFAR1DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4242474-A | A POLYHYDROXY ACRYLIC ESTER REACTED WITH AN ISOCYANATE TERMINATED POLYOXYALKYLENE GLYCOL; BIOPOLYMERS | TERUMO CORPORATION (JP) | 1980-12-30 | — | — | US | disclosed |