SCHEMBL477487

SCHEMBL477487

OCc1cccc(-c2cccs2)c1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRMT6 Q96LA8 1/20 0.63
FYN P06241 1/20 0.54
PRKCI P41743 1/20 0.53
LTA4H P09960 1/20 0.52
CNR2 P34972 1/20 0.50
FFAR1 O14842 1/20 0.49
CYP17A1 P05093 1/20 0.46
CYP11B1 P15538 1/20 0.46
CYP11B2 P19099 1/20 0.46
KCNH2 Q12809 1/20 0.46
ALDH1A1 P00352 1/20 0.44
HSD17B1 P14061 1/20 0.43
HSD17B2 P37059 1/20 0.43
HDAC1 Q13547 1/20 0.43
DPP4 P27487 1/20 0.43
CYP2E1 P05181 1/20 0.43
CYP3A4 P08684 1/20 0.43
CYP2A6 P11509 1/20 0.43
CYP2C9 P11712 1/20 0.43
CYP2B6 P20813 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5765234 0.82 LTA4H (0.68) PRMT6FYNLTA4HFFAR1CYP17A1
SCHEMBL4171352 0.81 PRMT6 (0.63) PRMT6FYNLTA4HFFAR1CYP17A1
SCHEMBL111078 0.81 LTA4H (0.72) PRMT6LTA4HFFAR1CYP17A1CYP11B1
SCHEMBL7499623 0.81 PRMT6 (0.63) PRMT6FYNLTA4HFFAR1CYP17A1
SCHEMBL158066 0.81 PRMT6 (0.68) PRMT6LTA4HFFAR1CYP17A1CYP11B1
SCHEMBL6393707 0.80 FFAR1 (0.57) PRMT6LTA4HFFAR1ALDH1A1HDAC1
SCHEMBL1334921 0.80 KCNH2 (0.59) PRMT6LTA4HCYP17A1CYP11B1CYP11B2
SCHEMBL6601600 0.79 PRMT6 (0.64) PRMT6FYNLTA4HFFAR1CYP17A1
SCHEMBL11482011 0.79 PRMT6 (0.59) PRMT6LTA4HFFAR1CYP17A1CYP11B1
SCHEMBL21408614 0.79 PRMT6 (0.64) PRMT6LTA4HFFAR1CYP17A1CYP11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8563786-B2 Method for producing optically active alcohol MITSUI CHEMICALS, INC. (JP) 2013-10-22 US disclosed
US-20120088938-A1 METHOD FOR PRODUCING OPTICALLY ACTIVE ALCOHOL AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2012-04-12 US disclosed
EP-2412694-A1 PROCESS FOR PRODUCING OPTICALLY ACTIVE ALCOHOL Mitsui Chemicals, Inc. (JP) 2012-02-01 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120088938-A1 METHOD FOR PRODUCING OPTICALLY ACTIVE ALCOHOL ADH1A, ADH1C, FHIT PRMT6 3799/4885FYN 4689/4885PRKCI 4409/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.