SCHEMBL114840

SCHEMBL114840

COC(N)c1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 2/20 0.50
F2 P00734 1/20 0.50
ADRA2A P08913 1/20 0.44
ADRA2C P18825 1/20 0.44
LMNA P02545 1/20 0.44
HIF1A Q16665 1/20 0.44
KDM4E B2RXH2 1/20 0.44
ALDH1A1 P00352 1/20 0.43
KMT2A Q03164 1/20 0.41
TAAR1 Q96RJ0 3/20 0.41
HTR2A P28223 1/20 0.40
SCN4A P35499 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL27904369 0.97 DPP4 (0.48) DPP4F2ADRA2AADRA2CLMNA
Ethylbenzene SCHEMBL15874120 0.85 TP53 (0.54) DPP4F2TAAR1
Benzaldehyde SCHEMBL8037482 0.84 ALDH1A1 (0.52) DPP4F2ALDH1A1KMT2A
Phenethylamine SCHEMBL10431641 0.82 TAAR1 (0.57) TAAR1HTR2A
SCHEMBL358554 0.78 DPP4 (0.55) DPP4F2ADRA2AADRA2CLMNA
SCHEMBL8131172 0.75 ADRA2A (0.46) DPP4F2ADRA2AADRA2CLMNA
SCHEMBL14344017 0.75 DPP4 (0.59) DPP4F2ADRA2AADRA2CLMNA
SCHEMBL15149664 0.75 ESR1 (0.48) LMNAHIF1AKDM4EALDH1A1KMT2A
SCHEMBL9638851 0.75 THRB (0.50) DPP4F2ADRA2AADRA2CLMNA
SCHEMBL12500605 0.75 CYP1A2 (0.53) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 822 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118806962-B Enzyme-responsive antibacterial hydrogel coating modified medical gauze and preparation method thereof 浙江大学 2025-03-18 CN claimed
CN-119595788-A Biomarker method for predicting curative effect of cyclosporine on aplastic anemia 宜兴市人民医院 2025-03-11 CN claimed
CN-118806962-A Enzyme-responsive antibacterial hydrogel coating modified medical gauze and preparation method thereof 浙江大学 2024-10-22 CN claimed
CN-118557747-A Conjugates of cell binding molecules and camptothecin analogs 杭州多禧生物科技有限公司 2024-08-30 CN claimed
US-12024483-B2 Synthesis method of hydroxybenzylamine TAIZHOU CHUANGYUAN INDUSTRIAL TECHNOLOGY CO., LTD (CN) 2024-07-02 US claimed
CN-117187133-A Culture medium for helicobacter pylori separation culture 苏州长柏生物科技有限公司 2023-12-08 CN claimed
CN-114105983-B Preparation and application of chiral 1,4,7, 10-tetraaza-2, 6-pyridine cycloparaffin derivative and metal chelate thereof 国科温州研究院(温州生物材料与工程研究所) 2023-08-11 CN claimed
CN-116082232-A Monoamine oxidase inhibitor, preparation method and application thereof 浙江海洋大学 2023-05-09 CN claimed
US-20220289664-A1 SYNTHESIS METHOD OF HYDROXYBENZYLAMINE TAIZHOU CHUANGYUAN INDUSTRIAL TECHNOLOGY CO., LTD (CN) 2022-09-15 US claimed
CN-112190556-B Compound sulfamethoxazole trimethoprim tablet and preparation method thereof 河北君临药业有限公司 2022-08-12 CN claimed
US-6423713-B1 Substituted pyrazoles as p38 kinase inhibitors G. D. SEARLE & COMPANY 2002-07-23 US claimed
CN-1323293-A The preparation of i(N)-substituted-hydroxycycloalkylamine derivatives SAMSUNG FINE CHEMICALS CO LTD (KR) 2001-11-21 CN claimed
EP-1144403-A1 SUBSTITUED PYRAZOLES AS P38 KINASE INHIBITORS G.D. SEARLE & CO. (US) 2001-10-17 EP claimed
EP-1114027-A1 THE PREPARATION OF N-SUBSTITUTED-HYDROXYCYCLOALKYLAMINE DERIVATIVES Samsung Fine Chemicals Co., Ltd. (KR) 2001-07-11 EP claimed
WO-2000031063-A1 SUBSTITUTED PYRAZOLES AS p38 KINASE INHIBITORS G.D. SEARLE & CO. (US) 2000-06-02 WO claimed
EP-1000055-A1 SUBSTITUTED PYRAZOLES AS p38 KINASE INHIBITORS G.D. Searle & Co. (US) 2000-05-17 EP claimed
WO-2000015610-A1 THE PREPARATION OF N-SUBSTITUTED-HYDROXYCYCLOALKYLAMINE DERIVATIVES SAMSUNG FINE CHEMICALS CO., LTD. (KR) 2000-03-23 WO claimed
WO-1998052940-A1 SUBSTITUTED PYRAZOLES AS p38 KINASE INHIBITORS G.D. SEARLE AND CO. (US) 1998-11-26 WO claimed
EP-0563145-A1 CHELATING AGENTS NYCOMED AS (NO) 1993-10-06 EP claimed
WO-1992011232-A1 CHELATING AGENTS NYCOMED IMAGING AS (NO) 1992-07-09 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12024483-B2 Synthesis method of hydroxybenzylamine HRH4, HRH2, HNMT DPP4 4230/4885F2 3471/4885ADRA2A 1126/4885
US-20220289664-A1 SYNTHESIS METHOD OF HYDROXYBENZYLAMINE HRH4, HRH2, HNMT DPP4 4230/4885F2 3471/4885ADRA2A 1126/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.