SCHEMBL358554

SCHEMBL358554

NC(OC(N)c1ccccc1)c1ccccc1

nearest known ligand 0.55

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 2/20 0.55
F2 P00734 1/20 0.55
HTR2A P28223 1/20 0.43
TAAR1 Q96RJ0 1/20 0.43
SCN4A P35499 2/20 0.43
ADRA2A P08913 1/20 0.42
ADRA2C P18825 1/20 0.42
LMNA P02545 1/20 0.42
HIF1A Q16665 1/20 0.42
KDM4E B2RXH2 1/20 0.42
TSHR P16473 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8603270 0.85 ADRA2A (0.46) DPP4F2TAAR1ADRA2AADRA2C
SCHEMBL20271341 0.85 DPP4 (0.46) DPP4F2HTR2ATAAR1SCN4A
SCHEMBL8131172 0.85 ADRA2A (0.46) DPP4F2TAAR1ADRA2AADRA2C
Ether SCHEMBL28580867 0.84 DPP4 (0.41) DPP4F2HTR2ATAAR1SCN4A
SCHEMBL2188803 0.78 DPP4 (0.50) DPP4F2HTR2ATAAR1SCN4A
SCHEMBL10289765 0.78 DPP4 (0.50) DPP4F2HTR2ATAAR1SCN4A
SCHEMBL114840 0.78 DPP4 (0.50) DPP4F2HTR2ATAAR1SCN4A
Hydrochloric Acid SCHEMBL27904369 0.76 DPP4 (0.48) DPP4F2TAAR1ADRA2AADRA2C
SCHEMBL1152103 0.76 SCN4A (0.48) DPP4F2HTR2ATAAR1SCN4A
Hydrochloric Acid SCHEMBL28458580 0.74 SCN4A (0.47) DPP4F2SCN4ATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 220 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260125418-A1 A COMPOUND AND ITS USE FOR DETECTING A DISEASE IN THE EXHALED BREATH OF A SUBJECT OWLSTONE MED LTD (GB) 2026-05-07 US claimed
EP-4598592-A1 A COMPOUND AND ITS USE FOR DETECTING A DISEASE IN THE EXHALED BREATH OF A SUBJECT Owlstone Medical Limited (GB) 2025-08-13 EP claimed
CN-120152745-A Compounds and their use for detecting diseases in exhaled breath of a subject 奥斯通医疗有限公司 2025-06-13 CN claimed
WO-2024074813-A1 A COMPOUND AND ITS USE FOR DETECTING A DISEASE IN THE EXHALED BREATH OF A SUBJECT OWLSTONE MEDICAL LIMITED (GB) 2024-04-11 WO claimed
CN-108997147-B Synthesis and use of N-alkyl amino benzene alkyl ether 深圳市广昌达石油添加剂有限公司 2020-12-22 CN claimed
EP-3166645-A1 SITE SELECTIVE CONJUGATION OF AN OLIGONUCLEOTIDE CONJUGATE OR A SMALL MOLECULE TO A METAL BINDING PROTEIN Affycon ApS (DK) 2017-05-17 EP claimed
WO-2016005474-A1 SITE SELECTIVE CONJUGATION OF AN OLIGONUCLEOTIDE CONJUGATE OR A SMALL MOLECULE TO A METAL BINDING PROTEIN AFFYCON APS (DK) 2016-01-14 WO claimed
US-7553816-B2 p-amidobenzylethers in drug delivery agents SEATTLE GENETICS, INC. (US) 2009-06-30 US claimed
US-7091186-B2 p-Amidobenzylethers in drug delivery agents SEATTLE GENETICS, INC. (US) 2006-08-15 US claimed
US-20030130189-A1 P-amidobenzylethers in drug delivery agents SEAGEN INC. 2003-07-10 US claimed
US-20030096743-A1 p-Amidobenzylethers in drug delivery agents SEATTLE GENETICS, INC. 2003-05-22 US claimed
WO-2003026577-A2 P-AMIDOBENZYLETHERS IN DRUG DELIVERY AGENTS SEATTLE GENETICS, INC. (US) 2003-04-03 WO claimed
US-20260139073-A1 Antigen Binding Proteins GLAXO GROUP LIMITED (GB) 2026-05-21 US disclosed
US-20260125418-A1 A COMPOUND AND ITS USE FOR DETECTING A DISEASE IN THE EXHALED BREATH OF A SUBJECT OWLSTONE MED LTD (GB) 2026-05-07 US disclosed
US-20260027147-A1 EXTRACELLULAR VESICLE-ASO CONSTRUCTS TARGETING CEBP/BETA LONZA SALES AG (CH) 2026-01-29 US disclosed
US-12466893-B2 Antigen binding proteins GLAXO GROUP LIMITED (GB) 2025-11-11 US disclosed
EP-1233970-A2 PROTECTING GROUPS USEFUL IN THE SYNTHESIS OF POLYSACCHARIDES, NATURAL PRODUCTS, AND COMBINATORIAL LIBRARIES MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2002-08-28 EP disclosed
US-6426421-B1 HALOGENATED BENZYL ETHER-BASED PROTECTING GROUPS FOR FUNCTIONAL GROUPS, OF ALCOHOLS, THIOLS, AMINES, CARBOXYLIC ACIDS, AND PHOSPHORIC ACIDS MASSACHUSETTS INSTITUTE OF TECHNOLOGY 2002-07-30 US disclosed
WO-2001038337-A2 PROTECTING GROUPS USEFUL IN THE SYNTHESIS OF POLYSACCHARIDES, NATURAL PRODUCTS, AND COMBINATORIAL LIBRARIES MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2001-05-31 WO disclosed
US-4156618-A REACTING ALDOSES WITH AN AMINE CONTAINING POLYMER ASAHI-DOW LIMITED (JP) 1979-05-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030130189-A1 P-amidobenzylethers in drug delivery agents ZYX, LPXN, NPBWR1 DPP4 325/4885F2 754/4885HTR2A 3410/4885
US-20260125418-A1 A COMPOUND AND ITS USE FOR DETECTING A DISEASE IN THE EXHALED BREATH OF A SUBJECT BRCA1, L3MBTL1, LMNA DPP4 2565/4885F2 254/4885HTR2A 4129/4885
US-20260027147-A1 EXTRACELLULAR VESICLE-ASO CONSTRUCTS TARGETING CEBP/BETA CEBPZ, OSBP, DIS3 DPP4 2867/4885F2 4882/4885HTR2A 4802/4885
US-12466893-B2 Antigen binding proteins CD40, TNFSF11, CD40LG DPP4 2859/4885F2 3110/4885HTR2A 3859/4885
US-20260139073-A1 Antigen Binding Proteins TNFSF11, TNFSF10, CD40 DPP4 4056/4885F2 1108/4885HTR2A 4080/4885
US-20030096743-A1 p-Amidobenzylethers in drug delivery agents ZYX, LPXN, NPBWR1 DPP4 330/4885F2 713/4885HTR2A 3080/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.