SCHEMBL11486192

SCHEMBL11486192

CC(=O)NOC(=O)c1c(I)c(N)c(I)c(CO)c1I

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7588477 0.75 CA2 (0.31)
SCHEMBL11220028 0.74 KDM4E (0.30)
SCHEMBL6226038 0.73 LMNA (0.36) LMNA
SCHEMBL7588474 0.71 LMNA (0.34) LMNA
SCHEMBL5682572 0.69 LMNA (0.56) LMNA
SCHEMBL7590137 0.68 KDM4E (0.30)
SCHEMBL7595632 0.68
SCHEMBL28367227 0.67 CA12 (0.40) LMNA
SCHEMBL9787569 0.66 LMNA (0.66) LMNA
SCHEMBL14958982 0.65 ALDH1A1 (0.37) LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4225577-A Ionic polyiodo benzene derivatives useful as X-ray contrast media GUERBET S.A. (FR) 1980-09-30 US disclosed