Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 3/20 | 0.67 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.67 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.36 |
| ▸ | ACLY | P53396 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.32 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | SPR | P35270 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6957228 | 0.83 | ABCB11 (0.70) | PTGS2ABCB11LMNAALDH1A1CYP1A2 | |
| SCHEMBL11488302 | 0.81 | ALDH1A1 (0.45) | PTGS2ABCB11LMNAALDH1A1CYP1A2 | |
| Zomepirac SCHEMBL11495798 | 0.81 | PTGS2 (1.00) | PTGS2ABCB11LMNAALDH1A1CYP1A2 | |
| Zomepirac SCHEMBL25735 | 0.81 | PTGS2 (1.00) | PTGS2ABCB11LMNAALDH1A1CYP1A2 | |
| Zomepirac SCHEMBL28350948 | 0.80 | PTGS2 (0.97) | PTGS2ABCB11LMNAALDH1A1CYP1A2 | |
| Zomepirac SCHEMBL43061 | 0.80 | PTGS2 (0.97) | PTGS2ABCB11LMNAALDH1A1CYP1A2 | |
| Zomepirac SCHEMBL9655800 | 0.80 | PTGS2 (0.97) | PTGS2ABCB11LMNAALDH1A1CYP1A2 | |
| Zomepirac SCHEMBL7204056 | 0.78 | PTGS2 (0.95) | PTGS2ABCB11LMNAALDH1A1CYP1A2 | |
| SCHEMBL10883943 | 0.77 | PTGS2 (0.66) | PTGS2ABCB11LMNAALDH1A1CYP1A2 | |
| SCHEMBL7674493 | 0.75 | PTGS2 (0.77) | PTGS2ABCB11LMNAALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4213905-A | Preparation of 5-aroyl-1-loweralkylpyrrole-2-acetic acid salts | MCNEILAB, INC. (US) | 1980-07-22 | — | — | US | disclosed |