Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.30 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11488381 | 0.82 | ABCB11 (0.68) | ALDH1A1LMNACYP1A2TSHRSMN1; SMN2 | |
| SCHEMBL11486351 | 0.81 | PTGS2 (0.67) | ALDH1A1LMNACYP1A2TSHRSMN1; SMN2 | |
| SCHEMBL11720886 | 0.79 | LMNA (0.35) | ALDH1A1LMNACYP1A2TSHRSMN1; SMN2 | |
| SCHEMBL11713188 | 0.72 | ABCB11 (0.52) | ALDH1A1LMNACYP1A2TSHRSMN1; SMN2 | |
| SCHEMBL11494142 | 0.71 | ALDH1A1 (0.48) | ALDH1A1LMNACYP1A2TSHRSMN1; SMN2 | |
| SCHEMBL11494138 | 0.70 | AKR1C3 (0.46) | ALDH1A1LMNACYP1A2TSHRSMN1; SMN2 | |
| SCHEMBL11495897 | 0.70 | ALDH1A1 (0.47) | ALDH1A1LMNACYP1A2TSHRSMN1; SMN2 | |
| SCHEMBL11770349 | 0.69 | ALDH1A1 (0.39) | ALDH1A1LMNACYP1A2TSHRSMN1; SMN2 | |
| SCHEMBL11769529 | 0.68 | SRD5A2 (0.41) | ALDH1A1LMNACYP1A2TSHRSMN1; SMN2 | |
| SCHEMBL11720309 | 0.68 | CYP1A2 (0.50) | ALDH1A1LMNACYP1A2TSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4213905-A | Preparation of 5-aroyl-1-loweralkylpyrrole-2-acetic acid salts | MCNEILAB, INC. (US) | 1980-07-22 | — | — | US | disclosed |