Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 2/20 | 0.52 |
| ▸ | DRD4 | P21917 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.47 |
| ▸ | PIM1 | P11309 | 4/20 | 0.46 |
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.46 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.46 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.46 |
| ▸ | CSNK2A3 | Q8NEV1 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10965123 | 0.83 | KDM4E (0.48) | DRD4HDAC8HDAC6HDAC3HDAC1 | |
| SCHEMBL11746320 | 0.83 | TBXAS1 (0.55) | TBXAS1LMNATP53PTGER2PIM1 | |
| SCHEMBL28246550 | 0.83 | TBXAS1 (0.55) | TBXAS1LMNATP53PTGER2PIM1 | |
| SCHEMBL16901848 | 0.80 | TBXAS1 (0.52) | TBXAS1HDAC3HDAC1HDAC2LMNA | |
| SCHEMBL10968431 | 0.78 | HDAC6 (0.54) | DRD4HDAC8HDAC6HDAC3HDAC1 | |
| SCHEMBL5599540 | 0.78 | ALDH1A1 (0.68) | LMNATP53HPGDALDH1A1KDM4E | |
| SCHEMBL7545069 | 0.77 | DRD4 (0.68) | DRD4ALDH1A1KDM4EGLAL3MBTL1 | |
| SCHEMBL22601122 | 0.77 | SLC16A3 (0.53) | TBXAS1LMNATP53PIM1CSNK2A1 | |
| SCHEMBL23512544 | 0.75 | LMNA (0.48) | TBXAS1LMNATP53PIM1CSNK2A1 | |
| SCHEMBL11493953 | 0.74 | LMNA (0.66) | TBXAS1LMNATP53PIM1CSNK2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4238487-A | ANTISECRETORY AGENTS | MERCK & CO., INC. (US) | 1980-12-09 | — | — | US | disclosed |