Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | PIM1 | P11309 | 5/20 | 0.49 |
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.49 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.49 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.49 |
| ▸ | CSNK2A3 | Q8NEV1 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | FLT3 | P36888 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11746320 | 0.87 | TBXAS1 (0.55) | TBXAS1LMNATP53PIM1CSNK2A1 | |
| SCHEMBL16901849 | 0.83 | NPC1 (0.50) | NPC1ALDH1A1POLBRAB9ASMN1; SMN2 | |
| SCHEMBL16903621 | 0.80 | TBXAS1 (0.49) | TBXAS1LMNATP53PIM1CSNK2A1 | |
| SCHEMBL11487550 | 0.80 | TBXAS1 (0.52) | TBXAS1LMNATP53PIM1CSNK2A1 | |
| SCHEMBL28246550 | 0.80 | TBXAS1 (0.55) | TBXAS1LMNATP53PIM1CSNK2A1 | |
| SCHEMBL23512544 | 0.78 | LMNA (0.48) | TBXAS1LMNATP53PIM1CSNK2A1 | |
| SCHEMBL22587927 | 0.78 | TBXAS1 (0.50) | TBXAS1LMNATP53PIM1CSNK2A1 | |
| SCHEMBL29355363 | 0.77 | ALDH1A1 (0.60) | LMNAPIM1CSNK2A1CSNK2A2CSNK2B | |
| SCHEMBL5599845 | 0.76 | PIM1 (0.54) | TBXAS1LMNATP53PIM1CSNK2A1 | |
| SCHEMBL17182687 | 0.76 | DRD2 (0.42) | TBXAS1LMNATP53NPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150197512-A1 | ANTIBACTERIAL AGENTS: ARYL MYXOPYRONIN DERIVATIVES | PROVID PHARMACEUTICALS INC. | 2015-07-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150197512-A1 | ANTIBACTERIAL AGENTS: ARYL MYXOPYRONIN DERIVATIVES | FBL, POLRMT, POLR1C | TBXAS1 1566/4885LMNA 514/4885TP53 2704/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.