Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 2/20 | 0.55 |
| ▸ | PIM1 | P11309 | 6/20 | 0.51 |
| ▸ | CSNK2A1 | P68400 | 4/20 | 0.51 |
| ▸ | CSNK2A2 | P19784 | 3/20 | 0.51 |
| ▸ | CSNK2B | P67870 | 3/20 | 0.51 |
| ▸ | CSNK2A3 | Q8NEV1 | 3/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | FLT3 | P36888 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.44 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5592937 | 0.86 | LMNA (0.65) | TBXAS1PIM1CSNK2A1CSNK2A2CSNK2B | |
| SCHEMBL11487550 | 0.83 | TBXAS1 (0.52) | TBXAS1PIM1CSNK2A1CSNK2A2CSNK2B | |
| SCHEMBL11746320 | 0.83 | TBXAS1 (0.55) | TBXAS1PIM1CSNK2A1CSNK2A2CSNK2B | |
| SCHEMBL10956152 | 0.81 | HTT (0.45) | TP53LMNAFLT3HPGDTSHR | |
| SCHEMBL16901848 | 0.80 | TBXAS1 (0.52) | TBXAS1PIM1CSNK2A1CSNK2A2CSNK2B | |
| SCHEMBL2197426 | 0.79 | PIM1 (0.74) | TBXAS1PIM1CSNK2A1CSNK2A2CSNK2B | |
| SCHEMBL2254319 | 0.79 | CYP4F2 (0.52) | LMNAHPGDTSHRKDM4EGLA | |
| SCHEMBL6407371 | 0.77 | FLT3 (0.76) | PIM1CSNK2A1CSNK2A2CSNK2BCSNK2A3 | |
| SCHEMBL28044374 | 0.77 | PIM1 (0.56) | TBXAS1PIM1CSNK2A1CSNK2A2CSNK2B | |
| SCHEMBL16903621 | 0.76 | TBXAS1 (0.49) | TBXAS1PIM1CSNK2A1CSNK2A2CSNK2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104693193-B | Aryl methoxy isoindoline derivative and composition and their application method including it | 细胞基因公司 | 2018-09-18 | — | — | CN | disclosed |