Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | LTA4H | P09960 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11487323 | 0.90 | LTA4H (0.56) | ALDH1A1LTA4HMEN1KMT2APTGS2 | |
| SCHEMBL11488495 | 0.88 | ALDH1A1 (0.53) | ALDH1A1LTA4HMEN1KMT2AMAPT | |
| SCHEMBL11487622 | 0.88 | LTA4H (0.55) | ALDH1A1LTA4HMEN1KMT2APTGS2 | |
| SCHEMBL11487560 | 0.88 | HTT (0.55) | ALDH1A1LTA4HMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL11493698 | 0.88 | ALDH1A1 (0.44) | ALDH1A1MEN1KMT2ASLC6A4SLC6A3 | |
| SCHEMBL11494089 | 0.87 | ALDH1A1 (0.43) | ALDH1A1MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL11495745 | 0.87 | SLC6A4 (0.52) | ALDH1A1LTA4HMEN1KMT2AMAPT | |
| SCHEMBL11489481 | 0.87 | ALDH1A1 (0.49) | ALDH1A1LTA4HMEN1KMT2AMAPT | |
| SCHEMBL11496587 | 0.87 | LMNA (0.53) | ALDH1A1LTA4HMEN1KMT2APTGS2 | |
| SCHEMBL11489477 | 0.87 | ALDH1A1 (0.52) | ALDH1A1LTA4HMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4239759-A | Morpholino containing compounds, compositions and use thereof | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1980-12-16 | — | — | US | disclosed |
| US-4110447-A | Anti-inflammatory (halo-4-biphenylyl)-alkanolamines | MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) | 1978-08-29 | — | — | US | disclosed |