Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.55 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.55 |
| ▸ | PSMB1 | P20618 | 2/20 | 0.52 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.52 |
| ▸ | PSMB2 | P49721 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.50 |
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.50 |
| ▸ | DRD1 | P21728 | 1/20 | 0.50 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11487323 | 0.99 | LTA4H (0.56) | LTA4HPTGS2PSMB1PSMB5PSMB2 | |
| SCHEMBL11492606 | 0.92 | HRH3 (0.54) | LTA4HPTGS2PSMB1PSMB5PSMB2 | |
| SCHEMBL11487560 | 0.90 | HTT (0.55) | LTA4HPTGS2ALDH1A1LMNAHTT | |
| SCHEMBL11496587 | 0.88 | LMNA (0.53) | LTA4HPTGS2ALDH1A1LMNAHTT | |
| SCHEMBL11489477 | 0.88 | ALDH1A1 (0.52) | LTA4HPTGS2ALDH1A1LMNAHTT | |
| SCHEMBL11487553 | 0.88 | ALDH1A1 (0.49) | LTA4HPTGS2ALDH1A1LMNAHTT | |
| SCHEMBL11495711 | 0.88 | ALDH1A1 (0.55) | LTA4HPSMB1PSMB5PSMB2ALDH1A1 | |
| SCHEMBL11487164 | 0.88 | ALDH1A1 (0.55) | LTA4HPSMB1PSMB5PSMB2ALDH1A1 | |
| SCHEMBL11485688 | 0.88 | CHRM2 (0.50) | PSMB1PSMB5PSMB2ALDH1A1LMNA | |
| SCHEMBL11494176 | 0.88 | CHRM2 (0.50) | PSMB1PSMB5PSMB2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4239759-A | Morpholino containing compounds, compositions and use thereof | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1980-12-16 | — | — | US | disclosed |
| US-4110447-A | Anti-inflammatory (halo-4-biphenylyl)-alkanolamines | MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) | 1978-08-29 | — | — | US | disclosed |