Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MMP1 | P03956 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | MMP13 | P45452 | 1/20 | 0.42 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.42 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.42 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.42 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11487560 | 0.91 | HTT (0.55) | ALDH1A1MEN1KMT2ASLC6A4SLC6A3 | |
| SCHEMBL11496587 | 0.90 | LMNA (0.53) | ALDH1A1MEN1KMT2ASLC6A4SLC6A3 | |
| SCHEMBL11487323 | 0.90 | LTA4H (0.56) | ALDH1A1MEN1KMT2ASLC6A4SLC6A3 | |
| SCHEMBL11487622 | 0.88 | LTA4H (0.55) | ALDH1A1MEN1KMT2ASLC6A4SLC6A3 | |
| SCHEMBL11492517 | 0.88 | HTT (0.47) | ALDH1A1MEN1KMT2AL3MBTL1SLC6A4 | |
| SCHEMBL11496270 | 0.88 | ALDH1A1 (0.57) | ALDH1A1MEN1KMT2ALMNAMMP1 | |
| SCHEMBL11487553 | 0.87 | ALDH1A1 (0.49) | ALDH1A1MEN1KMT2ASLC6A4SLC6A3 | |
| SCHEMBL11487270 | 0.86 | ALDH1A1 (0.67) | ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL11490485 | 0.85 | SIGMAR1 (0.54) | ALDH1A1 | |
| SCHEMBL11492606 | 0.81 | HRH3 (0.54) | MEN1KMT2ALTA4HPTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4239759-A | Morpholino containing compounds, compositions and use thereof | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1980-12-16 | — | — | US | disclosed |
| US-4110447-A | Anti-inflammatory (halo-4-biphenylyl)-alkanolamines | MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) | 1978-08-29 | — | — | US | disclosed |