Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 16/20 | 0.49 |
| ▸ | DRD2 | P14416 | 10/20 | 0.48 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.46 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.46 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.46 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.46 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.46 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.46 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11485028 | 0.85 | SIGMAR1 (0.46) | SIGMAR1DRD2GRIN2DGRIN3BGRIN1 | |
| SCHEMBL357523 | 0.83 | SIGMAR1 (0.49) | SIGMAR1DRD2GRIN2DGRIN3BGRIN1 | |
| SCHEMBL10890076 | 0.72 | SIGMAR1 (0.39) | SMN1; SMN2SIGMAR1DRD2GRIN2DGRIN3B | |
| SCHEMBL11478910 | 0.71 | SIGMAR1 (0.41) | SMN1; SMN2SIGMAR1DRD2GRIN2DGRIN3B | |
| SCHEMBL8700031 | 0.71 | SIGMAR1 (0.53) | SIGMAR1DRD2GRIN2DGRIN3BGRIN1 | |
| SCHEMBL11479263 | 0.70 | SIGMAR1 (0.44) | SIGMAR1DRD2 | |
| SCHEMBL27468872 | 0.69 | SIGMAR1 (0.57) | SIGMAR1DRD2GRIN2DGRIN3BGRIN1 | |
| SCHEMBL8905733 | 0.68 | SIGMAR1 (0.51) | SIGMAR1DRD2GRIN2DGRIN3BGRIN1 | |
| SCHEMBL3887315 | 0.67 | SMN1; SMN2 (1.00) | SMN1; SMN2CYP2C9CYP2C19NPSR1MEN1 | |
| SCHEMBL11479112 | 0.66 | L3MBTL1 (0.38) | SMN1; SMN2CYP2C9CYP2C19NPSR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3969373-A | Fluorogenic 2-oxy-3(2H)-furanone materials | HOFFMANN-LA ROCHE INC. (US) | 1976-07-13 | — | — | US | claimed |
| US-4238589-A | A 1-TERT-AMINO-4-PHENYL-2-(CARBOXY-SUBSTITUTED PHENYL)-1-BUTEN-3,4-DIONE; CHEMICAL INTERMEDIATE | HOFFMANN-LA ROCHE INC. (US) | 1980-12-09 | — | — | US | disclosed |
| US-4045487-A | FLUOROGENIC REAGENTS | HOFFMANN-LA ROCHE INC. (US) | 1977-08-30 | — | — | US | disclosed |
| US-4038289-A | FLUORESCENT LABELING, BIOLOGICAL | HOFFMANN-LA ROCHE INC. (US) | 1977-07-26 | — | — | US | disclosed |
| US-4018884-A | Fluorogenic materials and labeling techniques | HOFFMANN-LA ROCHE INC. (US) | 1977-04-19 | — | — | US | disclosed |
| US-3969373-A | Fluorogenic 2-oxy-3(2H)-furanone materials | HOFFMANN-LA ROCHE INC. (US) | 1976-07-13 | — | — | US | disclosed |