SCHEMBL357523

SCHEMBL357523

COC1(c2ccccc2)OC=C(c2ccccc2)C1=O

nearest known ligand 0.49

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 19/20 0.49
DRD2 P14416 12/20 0.48
GRIN2D O15399 1/20 0.43
GRIN3B O60391 1/20 0.43
GRIN1 Q05586 1/20 0.43
GRIN2A Q12879 1/20 0.43
GRIN2B Q13224 1/20 0.43
GRIN2C Q14957 1/20 0.43
GRIN3A Q8TCU5 1/20 0.43
BACE1 P56817 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10890076 0.87 SIGMAR1 (0.39) SIGMAR1DRD2GRIN2DGRIN3BGRIN1
SCHEMBL11478910 0.86 SIGMAR1 (0.41) SIGMAR1DRD2GRIN2DGRIN3BGRIN1
SCHEMBL11479263 0.84 SIGMAR1 (0.44) SIGMAR1DRD2
SCHEMBL11488348 0.83 SMN1; SMN2 (0.50) SIGMAR1DRD2GRIN2DGRIN3BGRIN1
SCHEMBL11485028 0.80 SIGMAR1 (0.46) SIGMAR1DRD2GRIN2DGRIN3BGRIN1
SCHEMBL8700031 0.75 SIGMAR1 (0.53) SIGMAR1DRD2GRIN2DGRIN3BGRIN1
SCHEMBL27468872 0.72 SIGMAR1 (0.57) SIGMAR1DRD2GRIN2DGRIN3BGRIN1
SCHEMBL8905733 0.71 SIGMAR1 (0.51) SIGMAR1DRD2GRIN2DGRIN3BGRIN1
SCHEMBL9235508 0.63 SIGMAR1 (0.47) SIGMAR1DRD2GRIN2DGRIN3BGRIN1
SCHEMBL10745566 0.63 SMN1; SMN2 (0.69)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 173 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260092924-A1 NON-ENZYMATIC GLOW ASSAYS UNIVERSITY OF HOUSTON SYSTEM (US) 2026-04-02 US claimed
US-20220011315-A1 NON-ENZYMATIC GLOW ASSAYS UNIVERSITY OF HOUSTON SYSTEM (US) 2022-01-13 US claimed
EP-3877753-A1 NON-ENZYMATIC GLOW ASSAYS University of Houston System (US) 2021-09-15 EP claimed
EP-2102653-B9 METHOD AND KIT FOR TESTING WHETHER A SPECIFIC PLANT HAS BEEN EXPOSED TO A SPECIFIC PESTICIDE UNIV AARHUS (DK) 2014-12-31 EP claimed
EP-2102653-B1 METHOD AND KIT FOR TESTING WHETHER A SPECIFIC PLANT HAS BEEN EXPOSED TO A SPECIFIC PESTICIDE UNIV AARHUS (DK) 2014-08-13 EP claimed
EP-2102654-B1 METHOD AND KIT FOR DETECTING HERBICIDE RESISTANCE IN PLANTS UNIV AARHUS (DK) 2014-08-13 EP claimed
US-20100150842-A1 Method and Kit for Detecting Resistance in Living Organisms AARHUS UNIVERSITET (DK) 2010-06-17 US claimed
US-20100047176-A1 Method and Kit for Testing Stress Effects in Living Organisms AARHUS UNIVERSITET (DK) 2010-02-25 US claimed
EP-2102653-A1 A METHOD AND KIT FOR TESTING STRESS EFFECTS IN LIVING ORGANISM Aarhus Universitet (DK) 2009-09-23 EP claimed
EP-2102654-A1 METHOD AND KIT FOR DETECTING RESISTANCE IN LIVING ORGANISMS Aarhus Universitet (DK) 2009-09-23 EP claimed
EP-1282415-A2 COMPOUNDS AND METHODS FOR REGULATING BACTERIAL GROWTH AND PATHOGENESIS Princeton University Office of Techology Licensing & I.P. (US) 2003-02-12 EP claimed
WO-2001085664-A2 COMPOUNDS AND METHODS FOR REGULATING BACTERIAL GROWTH AND PATHOGENESIS PRINCETON UNIVERSITY (US) 2001-11-15 WO claimed
US-4576912-A Fluoroimmunoassaying TECHNICON INSTRUMENTS CORPORATION (US) 1986-03-18 US claimed
EP-0011107-B1 METHOD FOR THE DETERMINATION OF AN AMINO ACID OR AN AMINO SULFONIC ACID F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) 1983-06-22 EP claimed
US-4272505-A Competitive binding analysis by fluorescence TECHNICON INSTRUMENTS CORPORATION (US) 1981-06-09 US claimed
EP-0011107-A1 Method for the determination of an amino acid or an amino sulfonic acid F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) 1980-05-28 EP claimed
US-4203967-A Diagnostic test for malabsorption HOFFMANN-LA ROCHE INC. (US) 1980-05-20 US claimed
US-4160818-A Fluorimetric immunoassay for diphenylhydantoin TECHNICON INSTRUMENTS CORPORATION (US) 1979-07-10 US claimed
US-4018884-A Fluorogenic materials and labeling techniques HOFFMANN-LA ROCHE INC. (US) 1977-04-19 US claimed
US-3969373-A Fluorogenic 2-oxy-3(2H)-furanone materials HOFFMANN-LA ROCHE INC. (US) 1976-07-13 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100047176-A1 Method and Kit for Testing Stress Effects in Living Organisms DDT, ACHE, WEE1 SIGMAR1 2021/4885DRD2 1482/4885GRIN2D 2989/4885
US-20260092924-A1 NON-ENZYMATIC GLOW ASSAYS LPO, HAO2, PPOX SIGMAR1 405/4885DRD2 3946/4885GRIN2D 1526/4885
US-20100150842-A1 Method and Kit for Detecting Resistance in Living Organisms DDT, NOTUM, ACHE SIGMAR1 1444/4885DRD2 2126/4885GRIN2D 3422/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.