Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11488537 | 0.89 | ALDH1A1 (0.43) | MEN1KMT2AALDH1A1CYP3A4L3MBTL1 | |
| SCHEMBL563886 | 0.84 | TP53 (0.41) | TP53ALDH1A1TSHRSMN1; SMN2LOXL2 | |
| SCHEMBL969878 | 0.78 | TSHR (0.46) | LMNAKMT2AALDH1A1L3MBTL1TSHR | |
| SCHEMBL752002 | 0.76 | KMT2A (0.41) | LMNAMEN1KMT2ATP53ALDH1A1 | |
| SCHEMBL562623 | 0.75 | LTA4H (0.39) | TP53ALDH1A1TSHRCYP2C19 | |
| SCHEMBL10841134 | 0.74 | TSHR (0.40) | KMT2ATP53ALDH1A1TSHRLOXL2 | |
| SCHEMBL19974320 | 0.73 | CA1 (0.43) | TP53ALDH1A1TDP1SMN1; SMN2NPC1 | |
| SCHEMBL7051790 | 0.73 | NPC1 (0.43) | LMNAMEN1KMT2AALDH1A1L3MBTL1 | |
| SCHEMBL14501654 | 0.72 | ALDH1A1 (0.39) | TP53ALDH1A1TSHRNPC1RAB9A | |
| SCHEMBL8483778 | 0.72 | IDO1 (0.42) | LMNAL3MBTL1MAPK1SMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4232010-A | CARDIOTONIC AND HYPOTENSIVE AGENTS | KANEBO, LTD. (JP) | 1980-11-04 | — | — | US | disclosed |