SCHEMBL562623

SCHEMBL562623

CO[PH](=O)Cc1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 1/20 0.39
TP53 P04637 1/20 0.39
ALDH1A1 P00352 3/20 0.38
TSHR P16473 3/20 0.37
MAOB P27338 1/20 0.37
F2 P00734 1/20 0.37
PLG P00747 1/20 0.37
ELANE P08246 1/20 0.37
CTSG P08311 1/20 0.37
CMA1 P23946 1/20 0.37
CTRC Q99895 1/20 0.37
CALM1 P0DP23 1/20 0.36
CYP2C19 P33261 1/20 0.35
EPHX2 P34913 1/20 0.34
CES2 O00748 1/20 0.34
CES1 P23141 1/20 0.34
AKR1B1 P15121 1/20 0.34
IDO1 P14902 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14501654 0.83 ALDH1A1 (0.39) LTA4HTP53ALDH1A1TSHRMAOB
SCHEMBL10841134 0.81 TSHR (0.40) TP53ALDH1A1TSHRMAOBF2
SCHEMBL8835472 0.78 CMA1 (0.42) ALDH1A1CMA1IDO1
SCHEMBL22188050 0.78 LOXL2 (0.46) MAOB
SCHEMBL27850533 0.78 TDP1 (0.41) ALDH1A1TSHRMAOB
SCHEMBL563886 0.78 TP53 (0.41) TP53ALDH1A1TSHRMAOBF2
SCHEMBL562844 0.77 KMT2A (0.41) LTA4HTSHRMAOBF2PLG
SCHEMBL27550741 0.77 TSHR (0.37) TP53ALDH1A1TSHRMAOBF2
SCHEMBL969878 0.76 TSHR (0.46) ALDH1A1TSHRMAOBCYP2C19IDO1
SCHEMBL11488455 0.75 LMNA (0.39) TP53ALDH1A1TSHRCYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2957514-B1 MULTI-LAYER BOTTLE AND METHOD FOR PRODUCING SAME MITSUBISHI GAS CHEMICAL CO (JP) 2021-08-04 EP disclosed
US-10144548-B2 Multi-layer bottle and method for producing same MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2018-12-04 US disclosed
CN-105899606-B Polyester and resin composition and its manufacture method 东丽株式会社 2018-04-17 CN disclosed
EP-3176212-A1 FLAME-RETARDANT RESIN COMPOSITION AND ARTICLE MOLDED FROM SAME Teijin Limited (JP) 2017-06-07 EP disclosed
CN-104995096-B Multi-layer bottle and manufacture method thereof 三菱瓦斯化学株式会社 2016-09-28 CN disclosed
CN-105899606-A Polyester resin composition and production method for same 东丽株式会社 2016-08-24 CN disclosed
US-20160001914-A1 MULTI-LAYER BOTTLE AND METHOD FOR PRODUCING SAME MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2016-01-07 US disclosed
EP-2957514-A1 MULTI-LAYER BOTTLE AND METHOD FOR PRODUCING SAME Mitsubishi Gas Chemical Company, Inc. (JP) 2015-12-23 EP disclosed
CN-104995096-A Multi-layer bottle and method for producing same MITSUBISHI GAS CHEMICAL CO 2015-10-21 CN disclosed
US-20120034480-A1 Catalyst for producing polyesters and polyester resin composition SAKAMOTO JUN (JP) 2012-02-09 US disclosed
US-7709594-B2 Polyester resin compositions, catalyst for polyester production, polyester film, and magnetic recording medium TORAY INDUSTRIES, INC. (JP) 2010-05-04 US disclosed
EP-1783171-A1 POLYTRIMETHYLENE TEREPHTHALATE Solotex Corporation (JP) 2007-05-09 EP disclosed
US-20060020103-A1 Polytrimethylene terephthalate SOLOTEX CORPORATION 2006-01-26 US disclosed
US-20050239929-A1 Polyester resin compositions, catalyst for polyester production, polyester film, and magnetic recording medium TORAY INDUSTRIES, INC. (JP) 2005-10-27 US disclosed
EP-1550683-A1 POLYESTER RESIN COMPOSITIONS, CATALYST FOR POLYESTER PRODUCTION, POLYESTER FILM, AND MAGNETIC RECORDING MEDIUM TORAY INDUSTRIES, INC. (JP) 2005-07-06 EP disclosed
US-4294989-A OPTICALLY ACTIVE HYDROGENATION CATALYSTS MONSANTO COMPANY (US) 1981-10-13 US disclosed
US-4265827-A METHYLCYCOHEXYL-O-ANISYLARSINE OPTICALLY ACTIVE CATALYST MONSANTO COMPANY (US) 1981-05-05 US disclosed
US-4261919-A OF BETA-SUBSTITUTED-ALPHA-ACYLAMIDO-ACRYLIC ACIDS TO YIELD OPTICALLY ACTIVE MIXTURE MONSANTO COMPANY (US) 1981-04-14 US disclosed
US-4124533-A HYDROGENATION CATALYSTS MONSANTO COMPANY (US) 1978-11-07 US disclosed
US-4005127-A L-Dopa process and intermediates MONSANTO COMPANY (US) 1977-01-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120034480-A1 Catalyst for producing polyesters and polyester resin composition PUF60, RPS24, SRP54 LTA4H 2430/4885TP53 1839/4885ALDH1A1 4666/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.