Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 7/20 | 0.63 |
| ▸ | LCK | P06239 | 3/20 | 0.58 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.49 |
| ▸ | HTR3B | O95264 | 1/20 | 0.49 |
| ▸ | HTR3A | P46098 | 1/20 | 0.49 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.49 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.49 |
| ▸ | TOP2A | P11388 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.42 |
| ▸ | CDK2 | P24941 | 2/20 | 0.42 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.40 |
| ▸ | CDK1 | P06493 | 1/20 | 0.40 |
| ▸ | CDK4 | P11802 | 1/20 | 0.40 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.40 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.40 |
| ▸ | CCND1 | P24385 | 1/20 | 0.40 |
| ▸ | CDK9 | P50750 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11484867 | 0.96 | MAPK8 (0.57) | MAPK8LCKHTR3EHTR3BHTR3A | |
| SCHEMBL8116882 | 0.85 | HTR3E (0.62) | MAPK8LCKHTR3EHTR3BHTR3A | |
| SCHEMBL8117091 | 0.77 | MAPK8 (1.00) | MAPK8LCKTOP2AALDH1A1SMN1; SMN2 | |
| SCHEMBL8118642 | 0.76 | MAPK8 (0.97) | MAPK8LCKTOP2AALDH1A1SMN1; SMN2 | |
| SCHEMBL8112977 | 0.74 | HTR3E (0.78) | MAPK8HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL120846 | 0.71 | MAPK8 (0.54) | MAPK8HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL13131265 | 0.71 | PTPN2 (0.59) | MAPK8LCKHTR3EHTR3BHTR3A | |
| SCHEMBL31746758 | 0.71 | MAPK8 (0.54) | MAPK8HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL30578099 | 0.71 | MAPK8 (0.54) | MAPK8HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL169235 | 0.71 | MAPK8 (0.54) | MAPK8HTR3EHTR3BHTR3AHTR3D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4200750-A | ANTIINFLAMMATORY AGENTS, FUNGICIDES, ANTIBODY INHIBITORS | WESTWOOD PHARMACEUTICALS INC. (US) | 1980-04-29 | — | — | US | claimed |