SCHEMBL11489486

SCHEMBL11489486

C=CCc1c(C)c(N)c(C)c(CC=C)c1O

nearest known ligand 0.37

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 1/20 0.37
MAOB P27338 1/20 0.34
KDM4E B2RXH2 2/20 0.33
GLA P06280 1/20 0.33
GAA P10253 1/20 0.33
ALDH1A1 P00352 1/20 0.32
MAPT P10636 1/20 0.32
HPGD P15428 1/20 0.32
ALOX15 P16050 1/20 0.32
HSD17B10 Q99714 1/20 0.32
GABRA1 P14867 1/20 0.31
GABRB2 P47870 1/20 0.31
CDC7 O00311 1/20 0.31
DBF4 Q9UBU7 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20088306 0.77 IMPDH2 (0.34) NPSR1MAOBKDM4EGLAGAA
SCHEMBL5810793 0.77 KDM4E (0.39) NPSR1MAOBKDM4EGLAGAA
SCHEMBL790695 0.75 GABRA1 (0.41) NPSR1KDM4EGLAGAAALDH1A1
SCHEMBL31330939 0.75 GABRA1 (0.41) NPSR1MAOBKDM4EGLAGAA
SCHEMBL6273663 0.73 GABRA1 (0.39) NPSR1KDM4EGLAGAAALDH1A1
SCHEMBL9028012 0.72 MAOB (0.34) MAOBKDM4EGLAGAAHPGD
SCHEMBL10401088 0.71 IMPDH2 (0.41) KDM4EGLAGAAALDH1A1MAPT
SCHEMBL11639061 0.71 GABRA1 (0.38) NPSR1KDM4EGLAGAAALDH1A1
SCHEMBL8190670 0.70 ALDH1A1 (0.39) NPSR1KDM4EGAAALDH1A1MAPT
SCHEMBL28716719 0.70 NPSR1 (0.38) NPSR1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0007987-A1 N-sulfenylated carbamoyloximino-1-methylthio butanes, process for their preparation and their use as insecticides BAYER AG (DE) 1980-02-20 EP disclosed
EP-0005780-A1 N,N'-asymmetrically substituted thio-bis-amines, process for their preparation and their use as insecticides, acaricides and nematocides BAYER AG (DE) 1979-12-12 EP disclosed