Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9028205 | 0.79 | MAOB (0.38) | MAOBHPGDKDM4EGLAGAA | |
| SCHEMBL11489486 | 0.72 | NPSR1 (0.37) | MAOBHPGDKDM4EGLAGAA | |
| SCHEMBL9027859 | 0.72 | KDM4E (0.35) | KDM4E | |
| SCHEMBL9571334 | 0.72 | MAOB (0.35) | MAOBKDM4EGLAGAA | |
| SCHEMBL9571652 | 0.72 | MAOB (0.33) | MAOBKDM4EGLAGAA | |
| SCHEMBL20088306 | 0.71 | IMPDH2 (0.34) | MAOBHPGDKDM4EGLAGAA | |
| SCHEMBL5810793 | 0.71 | KDM4E (0.39) | MAOBHPGDKDM4EGLAGAA | |
| SCHEMBL31330939 | 0.70 | GABRA1 (0.41) | MAOBHPGDKDM4EGLAGAA | |
| SCHEMBL790695 | 0.70 | GABRA1 (0.41) | HPGDKDM4EGLAGAA | |
| SCHEMBL8714563 | 0.68 | MAOB (0.33) | MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0445827-B1 | 4-Hydroxytetrahydropyran-2-one derivatives useful as cholesterol and lipid reducing agents | FUJIREBIO KK (JP) | 1996-09-25 | — | — | EP | disclosed |
| US-5149834-A | Anticholesterol agent and enzyme inhibitors, for curing arteriosclerosis | FUJIREBIO INC. (JP) | 1992-09-22 | — | — | US | disclosed |
| EP-0445827-A2 | 4-Hydroxytetrahydropyran-2-one derivatives useful as cholesterol and lipid reducing agents | FUJIREBIO INC. (JP) | 1991-09-11 | — | — | EP | disclosed |