Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | CTSD | P07339 | 1/20 | 0.46 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.46 |
| ▸ | CTSL | P07711 | 1/20 | 0.46 |
| ▸ | CTSB | P07858 | 1/20 | 0.46 |
| ▸ | CTSH | P09668 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | APP | P05067 | 1/20 | 0.43 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8884629 | 0.87 | MAPK1 (0.56) | TSHRMAPK1L3MBTL1MAPTPKM | |
| SCHEMBL5384243 | 0.87 | L3MBTL1 (0.61) | TSHRMAPK1L3MBTL1MAPTPKM | |
| Nitric Acid SCHEMBL11144683 | 0.82 | TSHR (0.50) | TSHRMAPK1L3MBTL1MAPTPKM | |
| SCHEMBL4930639 | 0.81 | L3MBTL1 (0.62) | TSHRMAPK1L3MBTL1MAPTPKM | |
| SCHEMBL9539004 | 0.80 | ALDH1A1 (0.44) | TSHRMAPK1L3MBTL1MAPTPKM | |
| SCHEMBL11741174 | 0.80 | MAPK1 (0.53) | TSHRMAPK1L3MBTL1MAPTPKM | |
| SCHEMBL3253899 | 0.79 | L3MBTL1 (0.77) | TSHRMAPK1L3MBTL1MAPTPKM | |
| Hydrochloric Acid SCHEMBL11533078 | 0.78 | MAPK1 (0.57) | TSHRMAPK1L3MBTL1MAPTPKM | |
| SCHEMBL11479021 | 0.78 | MAPT (0.59) | TSHRMAPK1L3MBTL1MAPTPKM | |
| SCHEMBL2329868 | 0.78 | L3MBTL1 (0.51) | TSHRMAPK1L3MBTL1MAPTPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4213982-A | USE TO PROMOTE GROWTH RATE OR FEED EFFICIENCY IN LIVESTOCK | E. R. SQUIBB & SONS, INC. (US) | 1980-07-22 | — | — | US | disclosed |
| US-4164580-A | 4H-s-Triazolo[4,3-a][1,5]benzodiazepin-5-ones as tranquilizers | E. R. SQUIBB & SONS, INC. (US) | 1979-08-14 | — | — | US | disclosed |
| US-4164498-A | CENTRAL NERVOUS SYSTEM DEPRESSANTS, TRANQUILIZERS, SEDATIVES, GROWTH PROMOTERS, ANTICONVULSANTS, MUSCLE RELAXANTS | E. R. SQUIBB & SONS, INC. (US) | 1979-08-14 | — | — | US | disclosed |
| US-4133809-A | DEPRESSANTS, TRANQUILIZERS, SEDATIVES, GROWTH PROMOTERS, ANTICONVULSANTS, MUSCLE RELAXANTS | E. R. SQUIBB & SONS, INC. (US) | 1979-01-09 | — | — | US | disclosed |
| US-4070355-A | CNS DEPRESSANTS, SEDATIVES, TRANQUILIZERS, MUSCLE RELAXANTS | E. R. SQUIBB & SONS, INC. (US) | 1978-01-24 | — | — | US | disclosed |
| US-4033947-A | CNS DEPRESSANTS, SEDATIVES, MUSCLE RELAXANTS | E. R. SQUIBB & SONS, INC. (US) | 1977-07-05 | — | — | US | disclosed |