SCHEMBL11492323

SCHEMBL11492323

Cc1ccccc1Oc1ccc(Cl)cc1C(=O)Cl

nearest known ligand 0.55

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.55
KMT2A Q03164 2/20 0.55
MAPT P10636 2/20 0.55
CCR2 P41597 3/20 0.46
ALDH1A1 P00352 1/20 0.46
SLC6A2 P23975 1/20 0.46
SLC6A4 P31645 1/20 0.46
SLC6A3 Q01959 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.45
HTR2C P28335 1/20 0.45
HTR2B P41595 1/20 0.45
AR P10275 1/20 0.44
SCN8A Q9UQD0 1/20 0.44
SCN10A Q9Y5Y9 1/20 0.44
CHRM1 P11229 1/20 0.43
PNLIP P16233 1/20 0.41
PTGDR2 Q9Y5Y4 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11483642 0.88 CCR2 (0.55) MEN1KMT2AMAPTCCR2ALDH1A1
SCHEMBL4441083 0.80 SLC6A2 (0.64) MEN1KMT2AMAPTSLC6A2SLC6A4
SCHEMBL11354413 0.80 CYP1A2 (0.56) MEN1KMT2AMAPTALDH1A1L3MBTL1
SCHEMBL4442222 0.77 HTR2C (0.54) MEN1KMT2AMAPTSLC6A2SLC6A4
SCHEMBL4508321 0.76 HTR2C (0.50) MEN1KMT2AMAPTALDH1A1SLC6A2
SCHEMBL257135 0.75 LMNA (0.61) MEN1KMT2AMAPTALDH1A1L3MBTL1
SCHEMBL25637031 0.75 PTGDR2 (0.50) MEN1KMT2AMAPTALDH1A1SLC6A2
SCHEMBL11490698 0.74 SLC6A2 (0.47) MEN1KMT2AMAPTALDH1A1SLC6A2
SCHEMBL11405282 0.73 HTT (0.69) CCR2ALDH1A1SLC6A2SLC6A4SLC6A3
SCHEMBL874097 0.73 ALDH1A1 (0.47) MAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4242121-A USING A PHENOXYBENZOIC ACID, ITS ESTER OR SALT IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1980-12-30 US disclosed