Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | KCNMA1 | Q12791 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.50 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.50 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3630423 | 0.93 | MRGPRX4 (0.58) | LMNAKCNMA1ALDH1A1MEN1KMT2A | |
| SCHEMBL11306685 | 0.86 | LMNA (0.63) | LMNAKCNMA1ALDH1A1MEN1KMT2A | |
| SCHEMBL1423874 | 0.85 | FLT1 (0.55) | LMNAKCNMA1ALDH1A1MEN1KMT2A | |
| SCHEMBL48961 | 0.85 | MRGPRX4 (0.64) | LMNAKCNMA1ALDH1A1MEN1KMT2A | |
| SCHEMBL364764 | 0.85 | ALDH1A1 (0.65) | LMNAKCNMA1ALDH1A1MEN1KMT2A | |
| SCHEMBL6542484 | 0.85 | LMNA (0.61) | LMNAKCNMA1ALDH1A1MEN1KMT2A | |
| SCHEMBL30100412 | 0.85 | MRGPRX4 (0.64) | LMNAKCNMA1ALDH1A1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL7210817 | 0.83 | MRGPRX4 (0.62) | LMNAKCNMA1ALDH1A1MEN1KMT2A | |
| SCHEMBL1095516 | 0.83 | MEN1 (0.64) | LMNAKCNMA1ALDH1A1MEN1KMT2A | |
| SCHEMBL726267 | 0.83 | MAPT (0.60) | LMNAKCNMA1ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 232 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108586447-B | Benzodiazepine compound and preparation method and application thereof | 中国人民解放军第四军医大学 | 2021-01-29 | — | — | CN | disclosed |
| WO-2019204449-A1 | K-RAS MODULATORS WITH A VINYL SULFONE MOIETY | THERAS, INC. (US) | 2019-10-24 | — | — | WO | disclosed |
| WO-2019204449-A1 | K-RAS MODULATORS WITH A VINYL SULFONE MOIETY | THERAS, INC. (US) | 2019-10-24 | — | — | WO | disclosed |
| WO-2019193062-A1 | SUBSTITUTED PYRROLIDINES AND THEIR USE | ABBVIE S.Á.R.L (LU) | 2019-10-10 | — | — | WO | disclosed |
| US-20170319516-A1 | NOVEL MITOCHONDRIAL UNCOUPLERS FOR TREATMENT OF METABOLIC DISEASES AND CANCER | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY | 2017-11-09 | — | — | US | disclosed |
| US-20170319516-A1 | NOVEL MITOCHONDRIAL UNCOUPLERS FOR TREATMENT OF METABOLIC DISEASES AND CANCER | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY | 2017-11-09 | — | — | US | disclosed |
| EP-3026046-A1 | THIAZOLES AS CANNABINOID RECEPTOR LIGANDS | AbbVie Inc. (US) | 2016-06-01 | — | — | EP | disclosed |
| WO-2016081599-A1 | NOVEL MITOCHONDRIAL UNCOUPLERS FOR TREATMENT OF METABOLIC DISEASES AND CANCER | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2016-05-26 | — | — | WO | disclosed |
| US-9340501-B2 | Marinopyrrole derivatives as anticancer agents | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. (US) | 2016-05-17 | — | — | US | disclosed |
| EP-2376462-B1 | THIAZOLES AS CANNABINOID RECEPTOR LIGANDS | ABBVIE INC (US) | 2015-12-16 | — | — | EP | disclosed |
| US-4158060-A | PSYCHOLOGICAL DISORDERS | SYNTHELABO (FR) | 1979-06-12 | — | — | US | disclosed |
| US-4158063-A | Acylamino(alkyl)benzene derivatives and process for preparing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-06-12 | — | — | US | disclosed |
| US-4113871-A | HYPOGLYCEMICALLY AND HYPOLIPIDEMICALLY ACTIVE DERIVATIVES OF PHENYL-ALKANE-CARBOXYLIC ACIDS | BOEHRINGER MANNHEIM GMBH (DE) | 1978-09-12 | — | — | US | disclosed |
| US-4021567-A | FOR PSYCHOSOMATIC AND PSYCHOTIC DISTURBANCES | SYNTHELABO (FR) | 1977-05-03 | — | — | US | disclosed |
| US-4010279-A | BIPHENYLOXY DERIVATIVES AND ANTIHYPERLIPIDEMIC USE | BOEHRINGER INGELHEIM GMBH (DT) | 1977-03-01 | — | — | US | disclosed |
| US-3984416-A | Substituted quinoline-8-carboxamido ethyl benzene-sulfonyl N-cyclopentylmethyl urea | HOECHST AKTIENGESELLSCHAFT (DT) | 1976-10-05 | — | — | US | disclosed |
| US-3965173-A | MULTISTAGE, METHYLATION OF 5-CHLOROSALICYLIC ACID | CHUBB FRANCIS L | 1976-06-22 | — | — | US | disclosed |
| US-3953449-A | ANALGESICS | SYNTHELABO (FR) | 1976-04-27 | — | — | US | disclosed |
| US-3932503-A | Benzenesulfonyl ureas | HOECHST AKTIENGESELLSCHAFT (DT) | 1976-01-13 | — | — | US | disclosed |
| US-3932658-A | Composition and method for lower blood sugar containing N-[4-(β-<2-methoxy-5-chloro-benzamido>-ethyl)-benzenesulfonyl]-N'-cyclopentyl-urea | HOECHST AKTIENGESELLSCHAFT (DT) | 1976-01-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170319516-A1 | NOVEL MITOCHONDRIAL UNCOUPLERS FOR TREATMENT OF METABOLIC DISEASES AND CANCER | HADHA, HADHB, TFAM | LMNA 3973/4885KCNMA1 3793/4885ALDH1A1 631/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.