Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11494201 | 0.85 | CNR2 (0.46) | CNR2NPC1TSHRRAB9ASMN1; SMN2 | |
| SCHEMBL11490044 | 0.84 | SIGMAR1 (0.42) | CNR2NPC1RAB9ASMN1; SMN2HDAC3 | |
| SCHEMBL11493894 | 0.82 | TMEM97 (0.44) | CNR2RAB9ASMN1; SMN2HDAC3HDAC1 | |
| SCHEMBL11495362 | 0.77 | HTT (0.49) | TSHRHDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL11491362 | 0.76 | HPGD (0.51) | NPC1RAB9ASMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL8867879 | 0.76 | ALDH1A1 (0.49) | CNR2RAB9ASMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL11495723 | 0.74 | USP2 (0.53) | TSHRRAB9ASMN1; SMN2HPGDLMNA | |
| SCHEMBL9418070 | 0.73 | ABCB11 (0.58) | TSHRHDAC1HDAC6LMNAMAPK1 | |
| SCHEMBL11490144 | 0.73 | HTT (0.56) | TSHRHDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL11490096 | 0.73 | POLB (0.55) | NPC1RAB9AHPGDLMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4202832-A | ANTILIPEMIC AGENTS | HOFFMANN-LA ROCHE INC. (US) | 1980-05-13 | — | — | US | disclosed |