Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11490047 | 0.86 | SIGMAR1 (0.42) | SIGMAR1CNR2CYP2C9CYP2C19POLB | |
| SCHEMBL11493894 | 0.84 | TMEM97 (0.44) | SIGMAR1CNR2POLBMEN1KMT2A | |
| SCHEMBL11494197 | 0.84 | CNR2 (0.48) | CNR2POLBMEN1KMT2AALDH1A1 | |
| SCHEMBL11495362 | 0.81 | HTT (0.49) | POLBMEN1KMT2ALMNAHTT | |
| SCHEMBL11491362 | 0.80 | HPGD (0.51) | SIGMAR1CYP2C9CYP2C19POLBMEN1 | |
| SCHEMBL8987627 | 0.79 | CYP2C9 (0.47) | SIGMAR1CYP2C9CYP2C19ALDH1A1HTT | |
| SCHEMBL11495723 | 0.78 | USP2 (0.53) | CYP2C9CYP2C19POLBKMT2AALDH1A1 | |
| SCHEMBL11490144 | 0.77 | HTT (0.56) | SIGMAR1MEN1KMT2AALDH1A1HTT | |
| SCHEMBL11490096 | 0.77 | POLB (0.55) | CYP2C9CYP2C19POLBMEN1KMT2A | |
| SCHEMBL11496728 | 0.77 | ALDH1A1 (0.46) | SIGMAR1CNR2CYP2C9CYP2C19POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4202832-A | ANTILIPEMIC AGENTS | HOFFMANN-LA ROCHE INC. (US) | 1980-05-13 | — | — | US | disclosed |