Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 4/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | SOS1 | Q07889 | 3/20 | 0.35 |
| ▸ | HSPB1 | P04792 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11499601 | 0.89 | LTA4H (0.39) | ARALDH1A1L3MBTL1LMNAMEN1 | |
| SCHEMBL11500352 | 0.86 | FFAR4 (0.38) | NFE2L2ARALDH1A1KDM4EHPGD | |
| SCHEMBL10550570 | 0.75 | ALDH1A1 (0.47) | NFE2L2CYP1A2CYP3A4CYP2C19ALDH1A1 | |
| SCHEMBL10549001 | 0.74 | ALDH1A1 (0.38) | NFE2L2CYP1A2CYP3A4CYP2C19HSPB1 | |
| SCHEMBL14437173 | 0.69 | AR (0.52) | ARSLC22A12 | |
| SCHEMBL6289867 | 0.68 | SOS1 (0.58) | NFE2L2CYP3A4SOS1HSPB1ALDH1A1 | |
| SCHEMBL351854 | 0.68 | SOS1 (0.58) | NFE2L2CYP3A4SOS1HSPB1ALDH1A1 | |
| SCHEMBL6290683 | 0.68 | SOS1 (0.58) | NFE2L2CYP3A4SOS1HSPB1ALDH1A1 | |
| SCHEMBL523438 | 0.68 | CYP19A1 (0.54) | CYP1A2CYP3A4CYP2C19ARALDH1A1 | |
| SCHEMBL10905892 | 0.68 | SCN9A (0.40) | CYP1A2CYP3A4CYP2C19SOS1HSPB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0001566-B1 | CYCLOBUTANECARBOXYLIC ACID DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS INSECTICIDES | BAYER AG (DE) | 1980-11-26 | — | — | EP | disclosed |
| EP-0001566-A2 | Cyclobutanecarboxylic acid derivatives, processes for their preparation and their use as insecticides | BAYER AG (DE) | 1979-05-02 | — | — | EP | disclosed |