Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 4/20 | 0.37 |
| ▸ | AR | P10275 | 2/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP3 | P08254 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | MMP14 | P50281 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11499601 | 0.88 | LTA4H (0.39) | FFAR4FFAR1ARALDH1A1MAPT | |
| SCHEMBL11498515 | 0.86 | NFE2L2 (0.36) | NFE2L2ARKDM4EALDH1A1HPGD | |
| SCHEMBL11288471 | 0.80 | FFAR4 (0.43) | FFAR4FFAR1NFE2L2MMP2MMP3 | |
| SCHEMBL10546476 | 0.80 | NFE2L2 (0.46) | NFE2L2MMP2MMP3MMP9MMP14 | |
| SCHEMBL10550056 | 0.77 | SLC6A2 (0.39) | NFE2L2ARSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6289347 | 0.74 | ALDH1A1 (0.54) | FFAR4FFAR1MMP2MMP3MMP9 | |
| SCHEMBL6290496 | 0.74 | ALDH1A1 (0.54) | FFAR4FFAR1MMP2MMP3MMP9 | |
| SCHEMBL7938427 | 0.74 | MAPT (0.46) | NFE2L2MMP2MMP3MMP9MMP14 | |
| SCHEMBL921025 | 0.72 | CYP19A1 (0.51) | FFAR4FFAR1ARMMP2MMP3 | |
| SCHEMBL6290322 | 0.72 | SMN1; SMN2 (0.58) | MMP2MMP3MMP9MMP14SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0001566-B1 | CYCLOBUTANECARBOXYLIC ACID DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS INSECTICIDES | BAYER AG (DE) | 1980-11-26 | — | — | EP | disclosed |
| EP-0001566-A2 | Cyclobutanecarboxylic acid derivatives, processes for their preparation and their use as insecticides | BAYER AG (DE) | 1979-05-02 | — | — | EP | disclosed |