Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | ANPEP | P15144 | 1/20 | 0.30 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.30 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7115792 | 0.98 | ALDH1A1 (0.33) | ALDH1A1TSHRMAPK1 | |
| Hydrochloric Acid SCHEMBL2515578 | 0.98 | ALDH1A1 (0.33) | ALDH1A1TSHRMAPK1 | |
| SCHEMBL1443231 | 0.79 | — | — | |
| Hydrochloric Acid SCHEMBL8103830 | 0.77 | CYP1A2 (0.30) | — | |
| Hydrochloric Acid SCHEMBL5703513 | 0.74 | — | — | |
| SCHEMBL4429218 | 0.74 | ALDH1A1 (0.35) | ALDH1A1TSHRMAPK1 | |
| Hydrochloric Acid SCHEMBL7429668 | 0.72 | — | — | |
| Hydrochloric Acid SCHEMBL5338641 | 0.72 | ALDH1A1 (0.33) | ALDH1A1TSHRMAPK1 | |
| SCHEMBL7484113 | 0.71 | — | — | |
| Hydrochloric Acid SCHEMBL4275672 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114315669-B | Methionine amide type small molecule lubricating oil additive and synthetic method and application thereof | 大连理工大学宁波研究院 | 2023-12-22 | — | — | CN | claimed |
| CN-115677727-B | Synthesis method of ceftazidime sulfate | 齐鲁安替制药有限公司 | 2023-11-24 | — | — | CN | claimed |
| CN-111995605-B | Chrysin cinnamate or its derivative and its preparation method | 五邑大学 | 2023-02-17 | — | — | CN | claimed |
| CN-115677727-A | Synthesis method of ceftaroline fosamil sulfate | 齐鲁安替制药有限公司 | 2023-02-03 | — | — | CN | claimed |
| CN-111233770-B | Chiral pyrazole derivative and synthesis method thereof | 南通大学 | 2022-12-27 | — | — | CN | claimed |
| EP-4043447-A1 | HALOGENATED TETRACYCLIC TRITERPENE DERIVATIVE, PREPARATION AND APPLICATION THEREOF | Shanghai King-X Biotech Co., Ltd. (CN) | 2022-08-17 | — | — | EP | claimed |
| US-20220177511-A1 | SERIES OF HALOGENATED TETRACYCLIC TRITERPENE DERIVATIVES AND THEIR PREPARATION AND APPLICATION | Shanghai Qingdong Biotechnology Co., Ltd. (CN) | 2022-06-09 | — | — | US | claimed |
| CN-114315669-A | Methionine amide micromolecule lubricating oil additive and synthetic method and application thereof | 大连理工大学宁波研究院 | 2022-04-12 | — | — | CN | claimed |
| CN-113416197-B | Carboxamide derivative, preparation method, pharmaceutical composition and application | 北京鑫开元医药科技有限公司 | 2021-12-28 | — | — | CN | claimed |
| CN-111249461-A | Preparation and application of phycocyanin-chlorin e6 covalent nanoparticles | 福州大学 | 2020-06-09 | — | — | CN | claimed |
| US-9359372-B2 | Hexahydrodibenzo[a,g]quinolizine compound, preparation method thereof, pharmaceutical composition and use thereof | SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) | 2016-06-07 | — | — | US | claimed |
| US-20150210711-A1 | HEXAHYDRODIBENZO[A,G]QUINOLIZINE COMPOUND, PREPARATION METHOD THEREOF, PHARMACEUTICAL COMPOSITION AND USE THEREOF | SHANGHAI INST MATERIA MEDICA (CN) | 2015-07-30 | — | — | US | claimed |
| US-20140088130-A1 | HEXAHYDRODIBENZO[A,G]QUINOLIZINE COMPOUND, PREPARATION METHOD THEREOF, PHARMACEUTICAL COMPOSITION AND USE THEREOF | SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) | 2014-03-27 | — | — | US | claimed |
| US-20130039904-A1 | GAMBOGIC ACID CYCLIZATION ANALOGUES, THEIR PREPARATION METHOD AND APPLICATION THEREOF | LIAONING LIFENG SCIENTIFIC & TECHNOLOGY DEVELOPMENT COMPANY LTD. (CN) | 2013-02-14 | — | — | US | claimed |
| US-20240182465-A1 | FUSED RING SUBSTITUTED SIX-MEMBERED HETEROCYCLIC COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | GENFLEET THERAPEUTICS (SHANGHAI) INC. (CN) | 2024-06-06 | — | — | US | disclosed |
| US-20240166664-A1 | TRIHETEROCYCLIC COMPOUND, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | SHANGHAI APEIRON THERAPEUTICS COMPANY LIMITED (CN) | 2024-05-23 | — | — | US | disclosed |
| EP-4303216-A1 | FUSED RING SUBSTITUTED SIX-MEMBERED HETEROCYCLIC COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | Genfleet Therapeutics (Shanghai) Inc. (CN) | 2024-01-10 | — | — | EP | disclosed |
| WO-2002070544-A2 | METHODS, COMPOSITIONS AND KITS FOR PRESERVING ANTIGENICITY | IDUN PHARMACEUTICALS, INC. (US) | 2002-09-12 | — | — | WO | disclosed |
| EP-0230166-A1 | Diagnostic reagents | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 1987-07-29 | — | — | EP | disclosed |
| WO-1987003372-A1 | DIAGNOSIS REAGENTS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE M (FR) | 1987-06-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140088130-A1 | HEXAHYDRODIBENZO[A,G]QUINOLIZINE COMPOUND, PREPARATION METHOD THEREOF, PHARMACEUTICAL COMPOSITION AND USE THEREOF | HTR5A, HTR1A, HTR2C | ALDH1A1 1083/4885TSHR 233/4885MAPK1 1862/4885 |
| US-20130039904-A1 | GAMBOGIC ACID CYCLIZATION ANALOGUES, THEIR PREPARATION METHOD AND APPLICATION THEREOF | IFNG, OXGR1, TLR7 | ALDH1A1 3646/4885TSHR 1715/4885MAPK1 3091/4885 |
| US-20220177511-A1 | SERIES OF HALOGENATED TETRACYCLIC TRITERPENE DERIVATIVES AND THEIR PREPARATION AND APPLICATION | AGTR1, VIP, AGT | ALDH1A1 292/4885TSHR 45/4885MAPK1 1657/4885 |
| US-20150210711-A1 | HEXAHYDRODIBENZO[A,G]QUINOLIZINE COMPOUND, PREPARATION METHOD THEREOF, PHARMACEUTICAL COMPOSITION AND USE THEREOF | HTR5A, HTR1A, HTR2C | ALDH1A1 1083/4885TSHR 233/4885MAPK1 1862/4885 |
| US-20240166664-A1 | TRIHETEROCYCLIC COMPOUND, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, WEE1, WEE2 | ALDH1A1 1500/4885TSHR 3151/4885MAPK1 1049/4885 |
| US-20240182465-A1 | FUSED RING SUBSTITUTED SIX-MEMBERED HETEROCYCLIC COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | WEE1, WEE2, HASPIN | ALDH1A1 3571/4885TSHR 4703/4885MAPK1 300/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.