Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A1 | P22736 | 1/20 | 0.47 |
| ▸ | SUCNR1 | Q9BXA5 | 5/20 | 0.47 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11641876 | 0.97 | ABCB11 (0.46) | NR4A1SUCNR1BDKRB1LMNAABCB11 | |
| SCHEMBL11458343 | 0.92 | PTGS2 (0.47) | BDKRB1LMNAABCB11PTGS1ADORA1 | |
| SCHEMBL11462832 | 0.82 | LMNA (0.41) | NR4A1BDKRB1LMNAMAPTCYP1A2 | |
| Hydrochloric Acid SCHEMBL11544674 | 0.79 | NR4A1 (0.60) | NR4A1LMNAABCB11PTGS1ADORA1 | |
| SCHEMBL11458546 | 0.79 | CXCL8 (0.46) | SUCNR1BDKRB1LMNAPTGS2ALDH1A1 | |
| SCHEMBL11460299 | 0.78 | ALDH1A1 (0.44) | ALDH1A1L3MBTL1MAPTCYP2C9CYP2C19 | |
| SCHEMBL11469095 | 0.78 | SRD5A2 (0.46) | LMNAALDH1A1NPSR1 | |
| SCHEMBL11445975 | 0.78 | NR4A1 (0.51) | NR4A1SUCNR1LMNAABCB11PTGS1 | |
| Hydrochloric Acid SCHEMBL11725673 | 0.77 | ABCB11 (0.50) | NR4A1SUCNR1LMNAABCB11PTGS1 | |
| SCHEMBL8502103 | 0.76 | BDKRB1 (0.37) | NR4A1BDKRB1LMNAALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4182774-A | Method of inhibiting blood platelet aggregation with 2-amino-3-(5- and 6-)benzoylphenylacetic acids, esters and metal salts thereof | A. H. ROBINS COMPANY, INCORPORATED (US) | 1980-01-08 | — | — | US | disclosed |