Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL719934 | 0.73 | EPHX1 (0.39) | ALDH1A1KDM4E | |
| SCHEMBL720552 | 0.73 | EPHX1 (0.39) | ALDH1A1KDM4E | |
| SCHEMBL11496670 | 0.72 | ALDH1A1 (0.56) | MAPTALDH1A1HRH3L3MBTL1MAPK1 | |
| SCHEMBL4564723 | 0.70 | ALDH1A1 (0.36) | MAPTALDH1A1HRH3L3MBTL1MAPK1 | |
| SCHEMBL21478037 | 0.69 | ALDH1A1 (0.33) | MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL540785 | 0.68 | HTT (0.39) | MAPTALDH1A1HRH3MAPK1NPSR1 | |
| SCHEMBL11501286 | 0.68 | KDM4E (0.43) | ALDH1A1HRH3KDM4E | |
| Bromide SCHEMBL5550542 | 0.67 | TSHR (0.40) | MAPTALDH1A1HRH3L3MBTL1MAPK1 | |
| SCHEMBL6680038 | 0.67 | ALDH1A1 (0.45) | MAPTALDH1A1HRH3L3MBTL1MAPK1 | |
| Bromide SCHEMBL5547799 | 0.67 | TSHR (0.40) | MAPTALDH1A1HRH3L3MBTL1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4212866-A | ANTIALLERGENS, ANTIINFLAMMATORY AGENTS, ANTIEDEMIC AGENTS | BOEHRINGER MANNHEIM GMBH (DE) | 1980-07-15 | — | — | US | disclosed |