Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.69 |
| ▸ | HTT | P42858 | 2/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.60 |
| ▸ | BDKRB1 | P46663 | 6/20 | 0.58 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | CCR9 | P51686 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | KCNA5 | P22460 | 4/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27995 | 0.88 | ALDH1A1 (0.74) | LMNAHTTALDH1A1CYP1A2HPGD | |
| SCHEMBL11182634 | 0.81 | LMNA (1.00) | LMNAHTTALDH1A1CYP1A2HPGD | |
| SCHEMBL12220857 | 0.81 | LMNA (0.81) | LMNAHTTALDH1A1CYP1A2HPGD | |
| SCHEMBL2534648 | 0.80 | BDKRB1 (0.73) | LMNAHTTALDH1A1CYP1A2HPGD | |
| SCHEMBL2534878 | 0.79 | LMNA (0.86) | LMNAHTTALDH1A1CYP1A2HPGD | |
| SCHEMBL13602386 | 0.79 | KMT2A (0.53) | LMNAHTTALDH1A1HPGDHSD17B10 | |
| SCHEMBL28289991 | 0.79 | BDKRB1 (0.74) | LMNAHTTALDH1A1CYP1A2HPGD | |
| SCHEMBL1688339 | 0.78 | METAP2 (0.71) | LMNAALDH1A1CYP1A2HPGDHSD17B10 | |
| SCHEMBL31305 | 0.78 | BDKRB1 (0.72) | LMNAHTTALDH1A1CYP1A2HPGD | |
| SCHEMBL2499921 | 0.77 | LMNA (0.67) | LMNAHTTALDH1A1CYP1A2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0000299-B1 | NOVEL DERIVATIVES OF SUBSTITUTED 2-BENZOYL-4-CHLORO-GLYCINANILIDES, THEIR PREPARATION AND THEIR USE AS MEDICINES. | PIERRE FABRE S.A. (FR) | 1980-11-12 | — | — | EP | claimed |
| EP-0000299-A1 | Novel derivatives of substituted 2-benzoyl-4-chloro-glycinanilides, their preparation and their use as medicines. | PIERRE FABRE S.A. (FR) | 1979-01-10 | — | — | EP | claimed |
| EP-0000299-B1 | NOVEL DERIVATIVES OF SUBSTITUTED 2-BENZOYL-4-CHLORO-GLYCINANILIDES, THEIR PREPARATION AND THEIR USE AS MEDICINES. | PIERRE FABRE S.A. (FR) | 1980-11-12 | — | — | EP | disclosed |
| EP-0000299-A1 | Novel derivatives of substituted 2-benzoyl-4-chloro-glycinanilides, their preparation and their use as medicines. | PIERRE FABRE S.A. (FR) | 1979-01-10 | — | — | EP | disclosed |