SCHEMBL11501514

SCHEMBL11501514

Brc1ccc(-c2[c]ccc(I)c2)cc1

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.33
MAPK1 P28482 1/20 0.33
CYP2A6 P11509 1/20 0.32
MAOB P27338 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16970612 0.81 ALDH1A1 (0.37) ALDH1A1MAPK1CYP2A6MAOB
SCHEMBL10449127 0.80 ACHE (0.32) ALDH1A1
SCHEMBL6189586 0.79 ALDH1A1 (0.33) ALDH1A1
SCHEMBL4466473 0.76 MAPK1 (0.33) ALDH1A1MAPK1CYP2A6MAOB
SCHEMBL3905765 0.76 AHR (0.33) ALDH1A1MAPK1CYP2A6MAOB
SCHEMBL11069373 0.76 KIF11 (0.39) ALDH1A1CYP2A6MAOB
SCHEMBL9099132 0.73 METAP2 (0.38)
SCHEMBL8169396 0.73 NQO2 (0.44) ALDH1A1
SCHEMBL4463655 0.72 MAPT (0.32) ALDH1A1MAPK1
SCHEMBL4468568 0.72 MEN1 (0.40) MAPK1MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4163022-A ANTIPLAQUE AGENTS COOPER LABORATORIES, INC. (US) 1979-07-31 US disclosed