Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 2/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 6/20 | 0.43 |
| ▸ | NAAA | Q02083 | 2/20 | 0.41 |
| ▸ | CASP2 | P42575 | 1/20 | 0.40 |
| ▸ | PRCP | P42785 | 1/20 | 0.40 |
| ▸ | SPHK1 | Q9NYA1 | 3/20 | 0.40 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.39 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.39 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.39 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.38 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.38 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11501586 | 0.81 | DNM1 (0.36) | DNM1EPHX1GRIN2DGRIN3BGRIN1 | |
| Ipexidine SCHEMBL11468017 | 0.77 | GNAI3 (0.52) | EPHX1NAAAPRCPSPHK1SIGMAR1 | |
| SCHEMBL13488633 | 0.76 | EPHX1 (0.52) | EPHX1NAAACASP2PRCPSPHK1 | |
| SCHEMBL12344278 | 0.74 | GRIN2D (0.53) | EPHX1NAAACASP2PRCPSPHK1 | |
| SCHEMBL11501681 | 0.73 | CHEK1 (0.34) | DNM1SIGMAR1 | |
| SCHEMBL11502019 | 0.73 | TSHR (0.39) | — | |
| SCHEMBL28379102 | 0.72 | EPHX1 (0.57) | EPHX1NAAACASP2 | |
| SCHEMBL30130591 | 0.72 | DNM1 (0.76) | DNM1NAAACASP2 | |
| SCHEMBL30130593 | 0.72 | DNM1 (0.76) | DNM1NAAACASP2 | |
| SCHEMBL11502078 | 0.72 | ALDH1A1 (0.36) | EPHX1NAAASPHK1GRIN2DGRIN3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4166827-A | DENTAL PLAQUE | COOPER LABORATORIES, INC. (US) | 1979-09-04 | — | — | US | claimed |
| US-4166827-A | DENTAL PLAQUE | COOPER LABORATORIES, INC. (US) | 1979-09-04 | — | — | US | disclosed |