Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 3/20 | 0.52 |
| ▸ | GNAO1 | P09471 | 3/20 | 0.52 |
| ▸ | GNAI1 | P63096 | 3/20 | 0.52 |
| ▸ | FPR3 | P25089 | 2/20 | 0.47 |
| ▸ | FPR2 | P25090 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | NAAA | Q02083 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | PRCP | P42785 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 4/20 | 0.41 |
| ▸ | SPHK1 | Q9NYA1 | 3/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11575634 | 0.81 | USP2 (0.52) | GNAI3GNAO1GNAI1FPR3FPR2 | |
| SCHEMBL11501703 | 0.77 | DNM1 (0.44) | GNAI3GNAO1GNAI1NAAAPRCP | |
| SCHEMBL11573574 | 0.76 | USP2 (0.40) | GNAI3GNAO1GNAI1FPR3FPR2 | |
| SCHEMBL11468097 | 0.75 | SIGMAR1 (0.52) | FPR3FPR2SMN1; SMN2EPHX1SIGMAR1 | |
| SCHEMBL11468030 | 0.75 | LMNA (0.40) | USP2KDM4ETP53SMN1; SMN2GAA | |
| SCHEMBL11574769 | 0.74 | SIGMAR1 (0.61) | FPR3FPR2TP53SIGMAR1 | |
| SCHEMBL13488633 | 0.73 | EPHX1 (0.52) | GNAI3GNAO1GNAI1NAAAPRCP | |
| SCHEMBL5531859 | 0.73 | FAAH (0.60) | USP2NAAATP53SMN1; SMN2 | |
| SCHEMBL5533634 | 0.73 | FAAH (0.60) | USP2NAAATP53SMN1; SMN2 | |
| SCHEMBL5524009 | 0.73 | FAAH (0.60) | USP2NAAATP53SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4209624-A | Process for preparing substituted bis(amidinoureas) | COOPER LABORATORIES, INC. (US) | 1980-06-24 | — | — | US | claimed |