Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.35 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.34 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.34 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.34 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.34 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.34 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.34 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.34 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.34 |
| ▸ | MLYCD | O95822 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11501703 | 0.81 | DNM1 (0.44) | DNM1EPHX1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL11573574 | 0.79 | USP2 (0.40) | GNAI3GNAO1GNAI1CYP2C19SMN1; SMN2 | |
| SCHEMBL11572940 | 0.74 | GNAI3 (0.43) | EPHX1DPP7GNAI3GNAO1GNAI1 | |
| SCHEMBL11501585 | 0.69 | MLYCD (0.34) | EPHX1DPP7GNAI3GNAO1GNAI1 | |
| SCHEMBL13755916 | 0.69 | FAAH (0.42) | DNM1EPHX1MAPK1KDM5AKDM5C | |
| SCHEMBL13756039 | 0.68 | FAAH (0.41) | DNM1EPHX1MAPK1KDM5AKDM5C | |
| SCHEMBL13756015 | 0.68 | FAAH (0.41) | DNM1EPHX1MAPK1KDM5AKDM5C | |
| SCHEMBL13756161 | 0.68 | FAAH (0.41) | DNM1EPHX1MAPK1KDM5AKDM5C | |
| SCHEMBL9683898 | 0.68 | ADH1B (0.47) | EPHX1MLYCDMAPK1 | |
| SCHEMBL18596029 | 0.68 | ADH1B (0.47) | EPHX1MLYCDMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4166827-A | DENTAL PLAQUE | COOPER LABORATORIES, INC. (US) | 1979-09-04 | — | — | US | claimed |
| US-4166827-A | DENTAL PLAQUE | COOPER LABORATORIES, INC. (US) | 1979-09-04 | — | — | US | disclosed |