Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 5/20 | 0.42 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11501930 | 0.91 | TMEM97 (0.46) | LMNAPOLBTSHRNPC1MEN1 | |
| SCHEMBL11668325 | 0.82 | CNR1 (0.50) | LMNATSHRNPC1MEN1KMT2A | |
| SCHEMBL11501627 | 0.82 | CNR1 (0.50) | LMNATSHRNPC1MEN1KMT2A | |
| SCHEMBL11674067 | 0.82 | CNR1 (0.50) | LMNATSHRNPC1MEN1KMT2A | |
| SCHEMBL11501942 | 0.75 | TP53 (0.56) | POLBMAPTSMN1; SMN2CNR1SIGMAR1 | |
| SCHEMBL11668323 | 0.70 | ALDH1A1 (0.50) | MEN1KMT2AGAAMAPTCNR1 | |
| SCHEMBL11501785 | 0.69 | TSHR (0.54) | LMNAPOLBTSHRNPC1MEN1 | |
| SCHEMBL2275794 | 0.69 | POLB (0.68) | LMNAPOLBNPC1MEN1KMT2A | |
| SCHEMBL11668293 | 0.69 | FPR2 (0.48) | MEN1KMT2ASIGMAR1 | |
| SCHEMBL11668446 | 0.68 | HTR3E (0.68) | LMNANPC1MEN1KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4166827-A | DENTAL PLAQUE | COOPER LABORATORIES, INC. (US) | 1979-09-04 | — | — | US | claimed |