Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 6/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.50 |
| ▸ | GBA1 | P04062 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | MC4R | P32245 | 2/20 | 0.50 |
| ▸ | RAD52 | P43351 | 2/20 | 0.50 |
| ▸ | HTR3A | P46098 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | SYNJ2 | O15056 | 1/20 | 0.50 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.50 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.50 |
| ▸ | MLNR | O43193 | 1/20 | 0.50 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.50 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | PGR | P06401 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11668325 | 1.00 | CNR1 (0.50) | CNR1SLC6A3ALOX15GBA1TP53 | |
| SCHEMBL11674067 | 1.00 | CNR1 (0.50) | CNR1SLC6A3ALOX15GBA1TP53 | |
| SCHEMBL11501930 | 0.87 | TMEM97 (0.46) | CNR1SLC6A3ALOX15GBA1TP53 | |
| SCHEMBL11668323 | 0.87 | ALDH1A1 (0.50) | CNR1SLC6A3HTR3AMEN1KMT2A | |
| SCHEMBL11501942 | 0.86 | TP53 (0.56) | CNR1TP53CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL11668293 | 0.85 | FPR2 (0.48) | MEN1KMT2AHDAC8 | |
| SCHEMBL11668524 | 0.85 | HDAC1 (0.51) | HTR3ALMNAHTTHTR3EHTR3B | |
| SCHEMBL11668446 | 0.85 | HTR3E (0.68) | TP53CYP3A4HTR3ALMNACYP1A2 | |
| SCHEMBL11501786 | 0.82 | LMNA (0.46) | CNR1SLC6A3ALOX15GBA1TP53 | |
| SCHEMBL11501546 | 0.82 | ALDH1A1 (0.62) | CNR1SLC6A3ALOX15GBA1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4022962-A | DENTAL PLAQUE INHIBITORS | COOPER LABORATORIES, INC. (US) | 1977-05-10 | — | — | US | claimed |
| US-4163022-A | ANTIPLAQUE AGENTS | COOPER LABORATORIES, INC. (US) | 1979-07-31 | — | — | US | disclosed |
| US-4115448-A | Carbamylguanidine antimicrobial compounds | COOPER LABORATORIES, INC. (US) | 1978-09-19 | — | — | US | disclosed |
| US-4115447-A | Carbamylguanidine antimicrobial compounds | COOPER LABORATORIES, INC. (US) | 1978-09-19 | — | — | US | disclosed |
| US-4022962-A | DENTAL PLAQUE INHIBITORS | COOPER LABORATORIES, INC. (US) | 1977-05-10 | — | — | US | disclosed |