Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | CNR1 | P21554 | 3/20 | 0.51 |
| ▸ | CACNA1G | O43497 | 5/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | DRD4 | P21917 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11668325 | 0.86 | CNR1 (0.50) | TP53MAPTCNR1SMN1; SMN2CYP1A2 | |
| SCHEMBL11674067 | 0.86 | CNR1 (0.50) | TP53MAPTCNR1SMN1; SMN2CYP1A2 | |
| SCHEMBL11501627 | 0.86 | CNR1 (0.50) | TP53MAPTCNR1SMN1; SMN2CYP1A2 | |
| SCHEMBL11574769 | 0.83 | SIGMAR1 (0.61) | TP53MAPTSIGMAR1DRD4 | |
| SCHEMBL11501930 | 0.79 | TMEM97 (0.46) | TP53MAPTCNR1SIGMAR1SMN1; SMN2 | |
| SCHEMBL10643366 | 0.75 | CACNA1G (0.69) | TP53MAPTCNR1CACNA1GSMN1; SMN2 | |
| SCHEMBL11501786 | 0.75 | LMNA (0.46) | TP53MAPTCNR1SIGMAR1SMN1; SMN2 | |
| SCHEMBL11572950 | 0.75 | KCNH2 (0.45) | TP53MAPTCNR1CACNA1GSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL10641983 | 0.74 | CACNA1G (0.67) | TP53MAPTCNR1CACNA1GSMN1; SMN2 | |
| SCHEMBL10641517 | 0.74 | MAPT (0.60) | TP53MAPTCNR1CACNA1GSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4110328-A | Bis-carbamylguanidinoazaalkane antimicrobial compounds | COOPER LABORATORIES, INC. (US) | 1978-08-29 | — | — | US | claimed |
| US-4166827-A | DENTAL PLAQUE | COOPER LABORATORIES, INC. (US) | 1979-09-04 | — | — | US | disclosed |