Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11501785 | 0.92 | TSHR (0.54) | TSHRPKMRAB9ATMEM97SIGMAR1 | |
| SCHEMBL11501626 | 0.89 | TSHR (0.49) | TSHRPKMRAB9ANPC1GAA | |
| SCHEMBL11668286 | 0.89 | TSHR (0.49) | TSHRPKMRAB9ANPC1GAA | |
| SCHEMBL11668321 | 0.89 | TSHR (0.49) | TSHRPKMRAB9ANPC1GAA | |
| SCHEMBL11501940 | 0.81 | CACNA1G (0.50) | SIGMAR1HRH3TP53 | |
| SCHEMBL11668287 | 0.75 | MEN1 (0.45) | LMNAHPGDMEN1KMT2A | |
| SCHEMBL11668317 | 0.75 | ALDH1A1 (0.49) | RAB9ANPC1GAAALDH1A1MAPT | |
| SCHEMBL11668516 | 0.75 | ALDH1A1 (0.45) | TSHRLTA4HGAAALDH1A1MAPT | |
| SCHEMBL13726874 | 0.75 | NPC1 (0.43) | TSHRRAB9ASIGMAR1NPC1GAA | |
| SCHEMBL11668443 | 0.74 | MEN1 (0.49) | TSHRRAB9ANPC1GAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4166827-A | DENTAL PLAQUE | COOPER LABORATORIES, INC. (US) | 1979-09-04 | — | — | US | claimed |