Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.40 |
| ▸ | SYNJ2 | O15056 | 1/20 | 0.40 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.40 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.40 |
| ▸ | MLNR | O43193 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11501626 | 1.00 | TSHR (0.49) | TSHRNPC1RAB9APKMALDH1A1 | |
| SCHEMBL11668321 | 1.00 | TSHR (0.49) | TSHRNPC1RAB9APKMALDH1A1 | |
| SCHEMBL11501927 | 0.89 | TSHR (0.51) | TSHRNPC1RAB9APKMALDH1A1 | |
| SCHEMBL11501785 | 0.86 | TSHR (0.54) | TSHRNPC1RAB9APKMALDH1A1 | |
| SCHEMBL11501940 | 0.86 | CACNA1G (0.50) | TP53CNR1 | |
| SCHEMBL11668317 | 0.85 | ALDH1A1 (0.49) | NPC1RAB9AALDH1A1MAPTGAA | |
| SCHEMBL11668287 | 0.85 | MEN1 (0.45) | HPGDLMNA | |
| SCHEMBL11668516 | 0.85 | ALDH1A1 (0.45) | TSHRALDH1A1MAPTGAAHSD17B10 | |
| SCHEMBL13726874 | 0.85 | NPC1 (0.43) | TSHRNPC1RAB9AALDH1A1MAPT | |
| SCHEMBL11668443 | 0.83 | MEN1 (0.49) | TSHRNPC1RAB9AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4022962-A | DENTAL PLAQUE INHIBITORS | COOPER LABORATORIES, INC. (US) | 1977-05-10 | — | — | US | claimed |