Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1G | O43497 | 7/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.46 |
| ▸ | CNR1 | P21554 | 2/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11668321 | 0.86 | TSHR (0.49) | TP53CNR1 | |
| SCHEMBL11668286 | 0.86 | TSHR (0.49) | TP53CNR1 | |
| SCHEMBL11501626 | 0.86 | TSHR (0.49) | TP53CNR1 | |
| SCHEMBL11501927 | 0.81 | TSHR (0.51) | TP53SIGMAR1HRH3 | |
| SCHEMBL11501785 | 0.78 | TSHR (0.54) | TP53SIGMAR1HRH3 | |
| SCHEMBL11574763 | 0.76 | SIGMAR1 (0.44) | SIGMAR1HRH3 | |
| SCHEMBL11668287 | 0.72 | MEN1 (0.45) | — | |
| SCHEMBL11668317 | 0.72 | ALDH1A1 (0.49) | — | |
| SCHEMBL11572949 | 0.72 | MAPT (0.44) | TP53CNR1 | |
| SCHEMBL11668516 | 0.72 | ALDH1A1 (0.45) | TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4110328-A | Bis-carbamylguanidinoazaalkane antimicrobial compounds | COOPER LABORATORIES, INC. (US) | 1978-08-29 | — | — | US | claimed |
| US-4166827-A | DENTAL PLAQUE | COOPER LABORATORIES, INC. (US) | 1979-09-04 | — | — | US | disclosed |