Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 4/20 | 0.38 |
| ▸ | DRD2 | P14416 | 3/20 | 0.38 |
| ▸ | CCR5 | P51681 | 2/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | HRH2 | P25021 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PTGIR | P43119 | 1/20 | 0.36 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11501940 | 0.76 | CACNA1G (0.50) | SIGMAR1HRH3 | |
| SCHEMBL27508524 | 0.69 | CYP3A4 (0.58) | MAPTCYP3A4GAAALDH1A1 | |
| SCHEMBL29668121 | 0.67 | EPHX2 (0.50) | SIGMAR1HRH3KDM4EMEN1ALDH1A1 | |
| SCHEMBL11564840 | 0.66 | NR1I2 (0.39) | CYP3A4MEN1ALDH1A1KMT2A | |
| SCHEMBL5144850 | 0.65 | NPC1 (0.46) | SIGMAR1CYP3A4ALDH1A1 | |
| SCHEMBL3744394 | 0.65 | SIGMAR1 (0.43) | SIGMAR1CYP3A4HRH4HRH3ALDH1A1 | |
| SCHEMBL11572836 | 0.64 | SIGMAR1 (0.37) | SIGMAR1CCR5MEN1ALDH1A1KMT2A | |
| SCHEMBL3646180 | 0.64 | CYP3A4 (0.65) | CYP3A4GAAMEN1ALDH1A1KMT2A | |
| SCHEMBL11738442 | 0.64 | CYP3A4 (0.60) | MAPTCYP3A4KDM4EGAAALDH1A1 | |
| SCHEMBL11561856 | 0.64 | ESR1 (0.40) | CYP3A4KDM4EGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4110328-A | Bis-carbamylguanidinoazaalkane antimicrobial compounds | COOPER LABORATORIES, INC. (US) | 1978-08-29 | — | — | US | claimed |