Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.32 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.32 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.31 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9728397 | 0.88 | ALDH1A1 (0.39) | ACELMNAALDH1A1POLBHSD17B10 | |
| SCHEMBL9331526 | 0.86 | ALDH1A1 (0.39) | LMNAALDH1A1POLBHSD17B10L3MBTL1 | |
| SCHEMBL2580570 | 0.85 | L3MBTL1 (0.47) | LMNAALDH1A1POLBHSD17B10L3MBTL1 | |
| SCHEMBL7276228 | 0.85 | L3MBTL1 (0.47) | LMNAALDH1A1POLBHSD17B10L3MBTL1 | |
| SCHEMBL10519344 | 0.83 | LDHA (0.43) | ACEALDH1A1L3MBTL1SMN1; SMN2TDP1 | |
| SCHEMBL11400130 | 0.83 | LDHA (0.43) | ACEALDH1A1L3MBTL1SMN1; SMN2TDP1 | |
| SCHEMBL11579749 | 0.83 | LDHA (0.43) | ACEALDH1A1L3MBTL1SMN1; SMN2TDP1 | |
| SCHEMBL2544891 | 0.75 | ALDH1A1 (0.39) | LMNAALDH1A1POLBHSD17B10L3MBTL1 | |
| SCHEMBL1928929 | 0.75 | L3MBTL1 (0.40) | LMNAALDH1A1POLBHSD17B10L3MBTL1 | |
| SCHEMBL1928928 | 0.75 | L3MBTL1 (0.40) | LMNAALDH1A1POLBHSD17B10L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4159263-A | INHIBIT RELEASE OF GROWTH HORMONE AND INSULIN | AMERICAN HOME PRODUCTS CORPORATION (US) | 1979-06-26 | — | — | US | disclosed |
| US-4123425-A | POLYPEPTIDES, HORMONE RELEASE INHIBITORS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1978-10-31 | — | — | US | disclosed |
| US-4100153-A | TREATMENT OF HYPERINSULINEMIA AND ACROMEGALY | AMERICAN HOME PRODUCTS CORPORATION (US) | 1978-07-11 | — | — | US | disclosed |