Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | ACE | P12821 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NR1D1 | P20393 | 1/20 | 0.39 |
| ▸ | BMP1 | P13497 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11579749 | 1.00 | LDHA (0.43) | LDHAL3MBTL1PPARGPPARATDP1 | |
| SCHEMBL10519344 | 1.00 | LDHA (0.43) | LDHAL3MBTL1PPARGPPARATDP1 | |
| SCHEMBL5494081 | 0.88 | LDHA (0.43) | LDHAL3MBTL1PPARGPPARATDP1 | |
| SCHEMBL9728397 | 0.88 | ALDH1A1 (0.39) | L3MBTL1PPARGPPARAACEALDH1A1 | |
| SCHEMBL2580570 | 0.87 | L3MBTL1 (0.47) | L3MBTL1MEN1KMT2AALDH1A1 | |
| SCHEMBL7276228 | 0.87 | L3MBTL1 (0.47) | L3MBTL1MEN1KMT2AALDH1A1 | |
| SCHEMBL11400678 | 0.85 | PPARG (0.41) | PPARGPPARAACEALDH1A1SMN1; SMN2 | |
| SCHEMBL11504081 | 0.83 | ACE (0.37) | L3MBTL1PPARGTDP1ACEALDH1A1 | |
| SCHEMBL11148899 | 0.83 | LDHA (0.43) | LDHAL3MBTL1PPARGPPARATDP1 | |
| SCHEMBL8893537 | 0.81 | LDHA (0.44) | LDHAL3MBTL1PPARGPPARATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0022621-A1 | Peptides related to somatostatin, their preparation and pharmaceutical compositions containing them | ELI LILLY AND COMPANY (US) | 1981-01-21 | — | — | EP | disclosed |
| EP-0011366-A2 | Synthetic peptides, their preparation, pharmaceutical formulations containing them and intermediates for their preparation | ELI LILLY AND COMPANY (US) | 1980-05-28 | — | — | EP | disclosed |
| US-4202802-A | PREFERENTIAL INHIBITION OF SCRETION OF GROWTH HORMONE | ELI LILLY AND COMPANY (US) | 1980-05-13 | — | — | US | disclosed |
| US-4199501-A | INHIBITORS OF SECRETION OF GROWTH HORMONE | ELI LILLY AND COMPANY (US) | 1980-04-22 | — | — | US | disclosed |
| US-4199500-A | INHIBITORS OF SECRETION OF GROWTH HORMONE | ELI LILLY AND COMPANY (US) | 1980-04-22 | — | — | US | disclosed |
| US-4100117-A | GASTROINTESTINAL DISORDERS | ELI LILLY AND COMPANY (US) | 1978-07-11 | — | — | US | disclosed |
| US-4093574-A | Somatostatin analogs and intermediates thereto | ELI LILLY AND COMPANY (US) | 1978-06-06 | — | — | US | disclosed |
| US-4087390-A | Somatostatin analogs and intermediates thereto | ELI LILLY AND COMPANY (US) | 1978-05-02 | — | — | US | disclosed |
| US-4076659-A | L-Val10 -somatostatin and intermediates thereto | ELI LILLY AND COMPANY (US) | 1978-02-28 | — | — | US | disclosed |
| US-4062816-A | D-Ala5 -somatostatin and intermediates thereto | ELI LILLY AND COMPANY (US) | 1977-12-13 | — | — | US | disclosed |
| US-4061607-A | Somatostatin analogs and intermediates thereto | ELI LILLY AND COMPANY (US) | 1977-12-06 | — | — | US | disclosed |
| US-4061626-A | GROWTH HORMONE STIMULANTS | ELI LILLY AND COMPANY (US) | 1977-12-06 | — | — | US | disclosed |