Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | ACE | P12821 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.36 |
| ▸ | STAT5B | P51692 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | AKT1 | P31749 | 2/20 | 0.34 |
| ▸ | MMP13 | P45452 | 1/20 | 0.33 |
| ▸ | SLC1A5 | Q15758 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2580570 | 0.90 | L3MBTL1 (0.47) | ALDH1A1LMNAPOLBHSD17B10L3MBTL1 | |
| SCHEMBL7276228 | 0.90 | L3MBTL1 (0.47) | ALDH1A1LMNAPOLBHSD17B10L3MBTL1 | |
| SCHEMBL10519344 | 0.88 | LDHA (0.43) | ALDH1A1L3MBTL1PPARGPPARAACE | |
| SCHEMBL11400130 | 0.88 | LDHA (0.43) | ALDH1A1L3MBTL1PPARGPPARAACE | |
| SCHEMBL11504081 | 0.88 | ACE (0.37) | ALDH1A1LMNAPOLBHSD17B10L3MBTL1 | |
| SCHEMBL11579749 | 0.88 | LDHA (0.43) | ALDH1A1L3MBTL1PPARGPPARAACE | |
| SCHEMBL2544891 | 0.87 | ALDH1A1 (0.39) | ALDH1A1LMNAPOLBHSD17B10L3MBTL1 | |
| SCHEMBL9331526 | 0.85 | ALDH1A1 (0.39) | ALDH1A1LMNAPOLBHSD17B10L3MBTL1 | |
| SCHEMBL9497492 | 0.82 | ALDH1A1 (0.39) | ALDH1A1LMNAPOLBHSD17B10L3MBTL1 | |
| SCHEMBL9497823 | 0.82 | ALDH1A1 (0.39) | ALDH1A1LMNAPOLBHSD17B10L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5169833-A | Analgesics | G. D. SEARLE & CO. (US) | 1992-12-08 | — | — | US | disclosed |
| WO-1991008759-A1 | ALKYL SUBSTITUTED CYCLIC PENICILLANIC ACID PENTAPAPTIDES | G.D. SEARLE & CO. (US) | 1991-06-27 | — | — | WO | disclosed |
| WO-1991009051-A1 | SUBSTITUTED CYCLIC PENICILLANIC ACID TETRAPEPTIDES | G.D. SEARLE & CO. (US) | 1991-06-27 | — | — | WO | disclosed |
| US-4224199-A | ANTIDIABETIC | MEYERS CHESTER A | 1980-09-23 | — | — | US | disclosed |