Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 4/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | HTR2C | P28335 | 2/20 | 0.34 |
| ▸ | HRH1 | P35367 | 2/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11504099 | 0.78 | SLC6A2 (0.42) | NISCHHTR2ACYP2D6SLC6A2SLC6A4 | |
| SCHEMBL5439029 | 0.76 | SMN1; SMN2 (0.54) | NISCHHTR2ACYP2D6SLC6A2SLC6A4 | |
| SCHEMBL5086903 | 0.71 | HTR2A (0.46) | NISCHHTR2ACYP2D6SLC6A2SLC6A4 | |
| SCHEMBL4837968 | 0.70 | PRCP (0.46) | HTR2ACYP2D6SLC6A2SLC6A4SMN1; SMN2 | |
| SCHEMBL10442292 | 0.69 | TSHR (0.46) | HTR2ASMN1; SMN2KDM1ATSHRCYP3A4 | |
| SCHEMBL24999225 | 0.67 | MAOA (0.41) | NISCHHTR2ACYP2D6SLC6A2SLC6A4 | |
| SCHEMBL3683946 | 0.67 | LMNA (0.39) | NISCHHTR2ACYP2D6SLC6A2SLC6A4 | |
| SCHEMBL3420534 | 0.67 | MAOA (0.41) | NISCHHTR2ACYP2D6SLC6A2SLC6A4 | |
| SCHEMBL22731139 | 0.67 | HTR2A (0.37) | NISCHHTR2ACYP2D6SLC6A2SLC6A4 | |
| SCHEMBL11419089 | 0.67 | SLC6A2 (0.37) | NISCHHTR2ACYP2D6SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4148968-A | COLORLESS TONER, A POLYMER OR CLAY AND A FATTY ACID OR DERIVATIVE | CANON KABUSHIKI KAISHA (JP) | 1979-04-10 | — | — | US | disclosed |