Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLTC | Q00610 | 2/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.41 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.41 |
| ▸ | PTGES | O14684 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | CTSV | O60911 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11428771 | 0.90 | CLTC (0.50) | CLTCPTPN1TP53AKR1C4AKR1C3 | |
| SCHEMBL9684699 | 0.87 | ALDH1A1 (0.42) | PTPN1TP53ALOX5TDP1CTSV | |
| SCHEMBL9077636 | 0.79 | CDK2 (0.47) | PTPN1ALOX5PTGESTSHRTDP1 | |
| SCHEMBL11505795 | 0.78 | PTPN1 (0.47) | CLTCPTPN1TP53AKR1C4AKR1C3 | |
| SCHEMBL24837592 | 0.77 | CLTC (0.47) | CLTCPTPN1TP53AKR1C4AKR1C3 | |
| SCHEMBL30247949 | 0.77 | CLTC (0.47) | CLTCPTPN1TP53AKR1C4AKR1C3 | |
| SCHEMBL23409361 | 0.77 | CLTC (0.47) | CLTCPTPN1TP53AKR1C4AKR1C3 | |
| SCHEMBL11420063 | 0.77 | ALDH1A1 (0.49) | PTPN1TP53TDP1CTSVCTSL | |
| SCHEMBL301592 | 0.77 | HSD17B10 (0.62) | PTPN1HSD17B10TSHRTDP1ALDH1A1 | |
| SCHEMBL9362663 | 0.77 | HSD17B10 (0.46) | PTPN1HSD17B10TDP1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112724349-B | Polymer and use thereof | 立邦涂料（中国）有限公司 | 2024-07-05 | — | — | CN | claimed |
| CN-114415472-B | Photosensitive resin composition containing polyimide precursor | 上海玟昕科技有限公司 | 2023-08-04 | — | — | CN | disclosed |
| CN-114442431-B | Photosensitive resin composition containing polyimide precursor | 上海玟昕科技有限公司 | 2023-08-04 | — | — | CN | disclosed |
| CN-114106341-A | Comb copolymer and preparation method and application thereof | 广州立邦涂料有限公司 | 2022-03-01 | — | — | CN | disclosed |
| US-7553336-B2 | Brightening direct dyes for keratin fibers and colorants containing these compounds | WELLA AG (DE) | 2009-06-30 | — | — | US | disclosed |
| US-7544215-B2 | Neutral and cationic naphthalene and colorants for keratin fibers containing these compounds | WELLA AG (DE) | 2009-06-09 | — | — | US | disclosed |
| US-20070151046-A1 | Neutral and cationic naphthalene and colorants for keratin fibers containing these compounds | Wella GmbH (DE) | 2007-07-05 | — | — | US | disclosed |
| US-20070119000-A1 | Brightening direct dyes for keratin fibers and colorants containing these compounds | WELLA AG (DE) | 2007-05-31 | — | — | US | disclosed |
| US-6664263-B2 | Potent unsymmetrical DNA bifunctional intercalators | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES | 2003-12-16 | — | — | US | disclosed |
| US-20030203916-A1 | 1,8-NAPHTHALIMIDE IMIDAZO{4,5,1-DE}ACRIDONES WITH ANTI-TUMOR ACTIVITY | HEALTH AND HUMAN SERVICES, THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE DEARTMENT OF | 2003-10-30 | — | — | US | disclosed |
| EP-1265898-B1 | 1,8-NAPHTHALIMIDE IMIDAZO 4,5,1- i de /i ]ACRIDONES WITH ANTI-TUMOR ACTIVITY | US GOV HEALTH & HUMAN SERV (US) | 2003-09-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070119000-A1 | Brightening direct dyes for keratin fibers and colorants containing these compounds | KRT18, MKI67, TUBB1 | CLTC 871/4885PTPN1 4666/4885TP53 2124/4885 |
| US-20070151046-A1 | Neutral and cationic naphthalene and colorants for keratin fibers containing these compounds | KRT18, NUP205, KPNA1 | CLTC 1029/4885PTPN1 3738/4885TP53 902/4885 |
| US-20030203916-A1 | 1,8-NAPHTHALIMIDE IMIDAZO{4,5,1-DE}ACRIDONES WITH ANTI-TUMOR ACTIVITY | MKI67, CDKN1A, CCNA1 | CLTC 4320/4885PTPN1 561/4885TP53 35/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.