Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLTC | Q00610 | 2/20 | 0.47 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | CDK2 | P24941 | 1/20 | 0.45 |
| ▸ | RORC | P51449 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.43 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.43 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CTSV | O60911 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11428771 | 0.86 | CLTC (0.50) | CLTCSORT1MAPTMEN1KMT2A | |
| SCHEMBL23409361 | 0.82 | CLTC (0.47) | CLTCSORT1MAPTMEN1KMT2A | |
| SCHEMBL30247949 | 0.82 | CLTC (0.47) | CLTCSORT1MAPTMEN1KMT2A | |
| SCHEMBL11420063 | 0.79 | ALDH1A1 (0.49) | MAPTMEN1KMT2AALDH1A1TDP1 | |
| SCHEMBL3895684 | 0.77 | CLTC (0.46) | CLTCSORT1MAPTMEN1KMT2A | |
| SCHEMBL2083961 | 0.75 | TSHR (0.60) | MAPTMEN1KMT2AALDH1A1TDP1 | |
| SCHEMBL11505795 | 0.74 | PTPN1 (0.47) | CLTCMEN1KMT2AALDH1A1TDP1 | |
| SCHEMBL28701181 | 0.74 | KMT2A (0.49) | CLTCSORT1MAPTMEN1KMT2A | |
| SCHEMBL7053647 | 0.74 | PKM (0.51) | SORT1MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL28823837 | 0.74 | PTPN1 (0.59) | MAPTMEN1KMT2AALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022250170-A9 | SMALL MOLECULE INHIBITORS OF KRAS MUTATED PROTEINS | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 2023-01-05 | — | — | WO | disclosed |